{"created":"2021-03-01T06:16:11.472243+00:00","id":11949,"links":{},"metadata":{"_buckets":{"deposit":"63acdf28-eae6-42f6-93e2-474980fd8a11"},"_deposit":{"id":"11949","owners":[],"pid":{"revision_id":0,"type":"depid","value":"11949"},"status":"published"},"_oai":{"id":"oai:niigata-u.repo.nii.ac.jp:00011949","sets":["453:456","471:537:538:1009"]},"item_7_alternative_title_1":{"attribute_name":"その他のタイトル","attribute_value_mlt":[{"subitem_alternative_title":"Histamine H_1 Receptor-induced Contraction in Rat Blood Vessels"}]},"item_7_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2006-11","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"11","bibliographicPageEnd":"650","bibliographicPageStart":"642","bibliographicVolumeNumber":"120","bibliographic_titles":[{"bibliographic_title":"新潟医学会雑誌"},{"bibliographic_title":"新潟医学会雑誌","bibliographic_titleLang":"en"}]}]},"item_7_description_4":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Rat blood vessels were reported not to constrict to histamine, and histamine-induced contraction at high concentration was mediated through α_1-adrenoceptors. In the present study, it was shown that rat arteries and veins constricted to histamine at low concentration (0.1-100μM) in a non-cumulative manner and that this contraction immediately desensitized. A histamine H_1 receptor antagonist, mepyramine, abolished this transient contraction completely, whereas cimetidine, phentolamine, reserpine and tetrodotoxin failed to inhibit the contraction, indicating that the contraction is mediated directly through H_1 receptor. H_1 receptor mRNA expression level detected by RT-PCR was quite parallel to H_1 receptor-mediated contraction in the vessels.","subitem_description_type":"Abstract"}]},"item_7_full_name_3":{"attribute_name":"著者別名","attribute_value_mlt":[{"nameIdentifiers":[{"nameIdentifier":"80589","nameIdentifierScheme":"WEKO"}],"names":[{"name":"Piao, Honglan"}]}]},"item_7_publisher_7":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"新潟医学会"}]},"item_7_rights_15":{"attribute_name":"権利","attribute_value_mlt":[{"subitem_rights":"本文データは学協会の許諾に基づきCiNiiから複製したものである"}]},"item_7_select_19":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_select_item":"publisher"}]},"item_7_source_id_11":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AN00182415","subitem_source_identifier_type":"NCID"}]},"item_7_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"00290440","subitem_source_identifier_type":"ISSN"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"朴, 紅蘭"}],"nameIdentifiers":[{"nameIdentifier":"80588","nameIdentifierScheme":"WEKO"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2019-08-07"}],"displaytype":"detail","filename":"110006483422.pdf","filesize":[{"value":"641.9 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"110006483422.pdf","url":"https://niigata-u.repo.nii.ac.jp/record/11949/files/110006483422.pdf"},"version_id":"f442d24c-d40f-4253-bef7-b767dba20d7a"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"Histamine","subitem_subject_scheme":"Other"},{"subitem_subject":"H_1 receptor","subitem_subject_scheme":"Other"},{"subitem_subject":"rat blood vessels","subitem_subject_scheme":"Other"},{"subitem_subject":"contraction","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"departmental bulletin paper","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"ラット血管平滑筋のヒスタミンH_1受容体を介する収縮反応","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"ラット血管平滑筋のヒスタミンH_1受容体を介する収縮反応"},{"subitem_title":"ラット血管平滑筋のヒスタミンH_1受容体を介する収縮反応","subitem_title_language":"en"}]},"item_type_id":"7","owner":"1","path":["456","1009"],"pubdate":{"attribute_name":"公開日","attribute_value":"2012-10-19"},"publish_date":"2012-10-19","publish_status":"0","recid":"11949","relation_version_is_last":true,"title":["ラット血管平滑筋のヒスタミンH_1受容体を介する収縮反応"],"weko_creator_id":"1","weko_shared_id":null},"updated":"2022-12-15T03:45:02.898427+00:00"}