{"_buckets": {"deposit": "05218217-ea2f-457f-b117-5b68f9c83553"}, "_deposit": {"id": "10948", "owners": [], "pid": {"revision_id": 0, "type": "depid", "value": "10948"}, "status": "published"}, "_oai": {"id": "oai:niigata-u.repo.nii.ac.jp:00010948", "sets": ["456", "985"]}, "item_7_alternative_title_1": {"attribute_name": "その他のタイトル", "attribute_value_mlt": [{"subitem_alternative_title": "Immunohistochemical Study for Isolated Tumor Cell (ITC) of Lymph Node in Intramucosal Colorectal Carcinoma"}]}, "item_7_biblio_info_6": {"attribute_name": "書誌情報", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "2008-11", "bibliographicIssueDateType": "Issued"}, "bibliographicIssueNumber": "11", "bibliographicPageEnd": "625", "bibliographicPageStart": "619", "bibliographicVolumeNumber": "122", "bibliographic_titles": [{"bibliographic_title": "新潟医学会雑誌"}, {"bibliographic_title": "新潟医学会雑誌", "bibliographic_titleLang": "en"}]}]}, "item_7_description_4": {"attribute_name": "抄録", "attribute_value_mlt": [{"subitem_description": "大腸粘膜内癌にはリンパ節転移例の報告はなく, 大腸粘膜内癌にはリンパ節転移能がないと考えられてきた. しかし従来の大腸粘膜内癌リンパ節転移に関する検索は, HE染色標本のみを元に行われたものであり, 免疫組織学的に同定されるりンパ節微小転移(isolated tumor cell: ITC)の有無については検討されていない. 本研究は, リンパ節郭清を伴う外科切除が施行され, 病変の全割切片による組織学的検索が行われた大腸粘膜内癌36例を対象に, 上皮性サイトケラチンCAM5.2免疫染色によりリンパ節ITCを検索し, ITCと原発巣粘膜内癌の組織学的因子との関連を検討した. 原発巣大腸粘膜内癌は全例が分化型(高分化･中分化)腺癌で, リンパ管侵襲･静脈侵襲, 蔟出のリンパ節転移リスク因子は陰性であり, 対象とした557個のリンパ節全てにITCは認められなかった. 以上のことから, 大腸粘膜内癌では免疫組織学的に同定されるITCすら存在せず, リンパ節転移能のない癌である可能性が高いことが再確認された. 大腸粘膜内癌では, 原発巣にリンパ節転移形成過程の第一段階である蔟出形成がなく, そのことがリンパ節転移が生じない主要因として推定された.", "subitem_description_type": "Abstract"}]}, "item_7_full_name_3": {"attribute_name": "著者別名", "attribute_value_mlt": [{"nameIdentifiers": [{"nameIdentifier": "74608", "nameIdentifierScheme": "WEKO"}], "names": [{"name": "Matsuzawa, Takeaki"}]}]}, "item_7_publisher_7": {"attribute_name": "出版者", "attribute_value_mlt": [{"subitem_publisher": "新潟医学会"}]}, "item_7_select_19": {"attribute_name": "著者版フラグ", "attribute_value_mlt": [{"subitem_select_item": "publisher"}]}, "item_7_source_id_11": {"attribute_name": "書誌レコードID", "attribute_value_mlt": [{"subitem_source_identifier": "AN00182415", "subitem_source_identifier_type": "NCID"}]}, "item_7_source_id_9": {"attribute_name": "ISSN", "attribute_value_mlt": [{"subitem_source_identifier": "00290440", "subitem_source_identifier_type": "ISSN"}]}, "item_creator": {"attribute_name": "著者", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "松澤, 岳晃"}], "nameIdentifiers": [{"nameIdentifier": "74607", "nameIdentifierScheme": "WEKO"}]}]}, "item_files": {"attribute_name": "ファイル情報", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2019-08-06"}], "displaytype": "detail", "download_preview_message": "", "file_order": 0, "filename": "122(11)_619-625.pdf", "filesize": [{"value": "1.0 MB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_free", "mimetype": "application/pdf", "size": 1000000.0, "url": {"label": "122(11)_619-625.pdf", "url": "https://niigata-u.repo.nii.ac.jp/record/10948/files/122(11)_619-625.pdf"}, "version_id": "a100d41c-774b-4056-94e0-2c9b52a8ee98"}]}, "item_keyword": {"attribute_name": "キーワード", "attribute_value_mlt": [{"subitem_subject": "大腸粘膜内癌", "subitem_subject_scheme": "Other"}, {"subitem_subject": "ITC", "subitem_subject_scheme": "Other"}, {"subitem_subject": "リンパ節転移", "subitem_subject_scheme": "Other"}, {"subitem_subject": "免疫染色", "subitem_subject_scheme": "Other"}, {"subitem_subject": "蔟出", "subitem_subject_scheme": "Other"}]}, "item_language": {"attribute_name": "言語", "attribute_value_mlt": [{"subitem_language": "jpn"}]}, "item_resource_type": {"attribute_name": "資源タイプ", "attribute_value_mlt": [{"resourcetype": "departmental bulletin paper", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": "大腸粘膜内癌のリンパ節ITC(isolsted tumor cell)の免疫組織学的検討", "item_titles": {"attribute_name": "タイトル", "attribute_value_mlt": [{"subitem_title": "大腸粘膜内癌のリンパ節ITC(isolsted tumor cell)の免疫組織学的検討"}, {"subitem_title": "大腸粘膜内癌のリンパ節ITC(isolsted tumor cell)の免疫組織学的検討", "subitem_title_language": "en"}]}, "item_type_id": "7", "owner": "1", "path": ["456", "985"], "permalink_uri": "http://hdl.handle.net/10191/28137", "pubdate": {"attribute_name": "公開日", "attribute_value": "2014-07-18"}, "publish_date": "2014-07-18", "publish_status": "0", "recid": "10948", "relation": {}, "relation_version_is_last": true, "title": ["大腸粘膜内癌のリンパ節ITC(isolsted tumor cell)の免疫組織学的検討"], "weko_shared_id": null}