@article{oai:niigata-u.repo.nii.ac.jp:00010818, author = {松本, 康男}, issue = {3}, journal = {新潟医学会雑誌, 新潟医学会雑誌}, month = {Mar}, note = {Purpose: Stereotactic radiotherapy (SRT) has been increasingly performed to treat peripheral Stage I non-small cell lung cancer (NSCLC) in many institutions. The preliminary results of treatment of Stage T1-T3N0M0 lung cancer using the Novalis radiotherapy system were analyzed. Method & Materials: Between July 2005 and June 2007, 185 patients with primary lung cancer were treated with the Novalis system. Excluding patients with local recurrence (post-operative or post-irradiation), advanced disease and poor performance status (KPS≧3), 141 patients (146 lesions) are the subject of this report. The disease was staged as T1N0M0, T2N0M0 and T3N0M0 in 101, 41 and 4 patients, respectively. SRT was performed using coplanar dynamic conformal arcs. All patients were received 48Gy to 60Gy (4 to 10 fractions) at the isocenter. Results: During follow up (median, 16.0 months; range, 3-31 months), pulmonary complications of National Cancer Institute-Common Toxicity Criteria (NCI-CTC) Grade≧2 were observed in 4 patients. Local progression occurred in 11 patients (7.6%), The 1-year&2-year overall survival rates were 96.2&92.0%, respectively. Conclusions: SRT using the Novalis shaped beam radiotherapy system is an effective and safe noninvasive treatment modality for early stage NSCLC.}, pages = {111--116}, title = {3 ノバリスによる肺癌の定位放射線治療の短期治療成績(超高精度放射線治療の進歩,第640回新潟医学会)}, volume = {123}, year = {2009} }