2024-03-29T08:01:38Z
https://niigata-u.repo.nii.ac.jp/oai
oai:niigata-u.repo.nii.ac.jp:00032030
2022-12-15T04:02:22Z
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麻酔下ウサギにおいて末梢および中枢性嚥下が顎反射に及ぼす影響
Effect of peripherally and cortically evoked swallows on jaw reflex responses in anesthetized rabbits
Effect of peripherally and cortically evoked swallows on jaw reflex responses in anesthetized rabbits
Suzuki, Taku
175092
Swallow
Jaw-opening reflex
Jaw-closing reflex
Superior laryngeal nerve
Cortical swallowing area
Rabbit
新潟大学
博士(歯学)
This study aimed to investigate whether the jaw-opening (JOR) and jaw-closing reflexes (JCR) are modulated during not only peripherally, but also centrally, evoked swallowing. Experiments were carried out on 24 adult male Japanese white rabbits. JORs were evoked by trigeminal stimulation at 1 Hz for 30 s. In the middle 10 s, either the superior laryngeal nerve (SLN) or cortical swallowing area (Cx) was simultaneously stimulated to evoke swallowing. The peak-to-peak JOR amplitude was reduced during the middle and late 10-s periods (i.e., during and after SLN or Cx stimulation), and the reduction was dependent on the current intensity of SLN/Cx stimulation: greater SLN/Cx stimulus current resulted in greater JOR inhibition. The reduction rate was significantly greater during Cx stimulation than during SLN stimulation. The amplitude returned to baseline 2 min after 10-s SLN/Cx stimulation. The effect of co-stimulation of SLN and Cx was significantly greater than that of SLN stimulation alone. There were no significant differences in any parameters of the JCR between conditions. These results clearly showed that JOR responses were significantly suppressed, not only during peripherally evoked swallowing but also during centrally evoked swallowing, and that the inhibitory effect is likely to be larger during centrally compared with peripherally evoked swallowing. The functional implications of these results are discussed.
学位の種類: 博士(歯学). 報告番号: 甲第4504号. 学位記番号: 新大院博(歯)甲第412号. 学位授与年月日: 平成30年9月20日
新大院博(歯)甲第412号
thesis
新潟大学
2018-09-20
2018-09-20
application/pdf
application/pdf
13101甲第4504号
https://niigata-u.repo.nii.ac.jp/record/32030/files/h30ndk412.pdf
https://niigata-u.repo.nii.ac.jp/record/32030/files/h30ndk412_a.pdf
eng
info:doi/10.1016/j.brainres.2018.05.002
(C) 2018 Elsevier B.V. All rights reserved.