2024-03-28T10:36:14Z
https://niigata-u.repo.nii.ac.jp/oai
oai:niigata-u.repo.nii.ac.jp:00023301
2022-12-15T03:53:34Z
453:456
471:537:538:1217
The endocrinological findings in the autopsied case of septic shock associated with severe hypoglycemia
著明な低血糖を呈した敗血症性ショックの一剖検例 : 内分泌所見について
著明な低血糖を呈した敗血症性ショックの一剖検例 : 内分泌所見について
星山, 真理
140462
岩渕, 三哉
140463
鬼島, 宏
140464
高木, 卯一
140465
septic shock
hypoglycemia
敗血症性ショック
低血糖
The autopsied case of septic shock associated with severe hypoglycemia was rarely reported. In this paper a case report was presented on a 67-year-old man who died of septic shock with hypoglycemia (BG 13mg/dl). The pathological diagnosis was hepatic cirrhosis and acute bacterial pneumonia. There was no evidence of insulinoma, β-cell hyperplasia and other endocrine organ abnormalities. Levels of serum IRI, growth hormone and plasma cortisol were elevated. Several mechanisms of hypoglycemia and hyperinsulinemia in this case are considered; (i) decreased hepatic glycogen storage due to the hepatic cirrhosis, (ii) increased catabolic state and glucose consumption in the peripheral tissues under the endotoxin shock state, (iii) inhibition of gluconeogenesis and acceleration of glucogenolysis in the liver, (iv) influence of the hepatic glucose metabolism induced by endotoxin, and (v) release and leakage of some hormones from shocked organs. Septic shock is critical and rapidly progressive.
departmental bulletin paper
新潟医学会
1988-10
application/pdf
新潟医学会雑誌
10
102
646
650
新潟医学会雑誌
AN00182415
00290440
https://niigata-u.repo.nii.ac.jp/record/23301/files/102(10)_646-650.pdf
jpn