2022-08-18T16:44:35Zhttps://niigata-u.repo.nii.ac.jp/oaioai:niigata-u.repo.nii.ac.jp:000219562021-03-01T13:29:46ZA Study on the Prediction of Toxemic Pregnancy妊娠中毒症発症予知に関する研究妊娠中毒症発症予知に関する研究吉村, 理133590toxemic pregnancypredictioncoagulation and fibrinolysis system妊娠中毒症予知凝固線溶系The pregnant women (344 cases) were divided into two groups. toxemic groups (59 cases) and non-toxemic groups (285 cases). The values for AT-III, platelet (PL), α_2-PI, FDP, Ht, uric acid (UA), NAG were measured simultaneously, and the statistical analysis was performed using linear discriminant analysis. We evaluated the diagnostic usefulness of discriminant, analysis employing 9 parameters for the prediction of toxemic pregnancy. Before 19 weeks, the functional formula, Y=-1.17+0.199NAG, was obtained by linear discriminant analysis method, with 66.1% for discrimination rate and 60.0% for predictive value. From 20 weeks to 29 weeks, the functional formula, Y=-3.68+0.065FDP+0.092PL+0.102NAG, was obtained by the analysis, with 67.8% for discrimination rate and 65.0% for predictive value. After 30 weeks, the functional formula, Y=-2.34+0.103FDP+0.219UA+0.095NAG, was obtained by the analysis, with 75.0% for discrimination rate and 65.2% for predictive value. The present, study demonstrated that the alterations in coagulation and fibrinolysis systems occurred before the onset of toxemic pregnancy. These data suggest that the discriminant analysis using 9 parameters may be effective clinically for the prediction of toxemic pregnancy.departmental bulletin paper新潟医学会1990-10application/pdf新潟医学会雑誌10104870876新潟医学会雑誌AN0018241500290440https://niigata-u.repo.nii.ac.jp/record/21956/files/104(10)_870-876.pdfjpn