2024-03-19T08:26:05Z
https://niigata-u.repo.nii.ac.jp/oai
oai:niigata-u.repo.nii.ac.jp:00021630
2022-12-15T03:52:07Z
453:456
471:537:538:1189
New Parameters in DIC : Ddimer, TAT, PIC
1) DICの新しい診断法 : Dダイマー, TAT, PIC(シンポジウム DIC-診断・治療の最近の動向, 第457回新潟医学会)
1) DICの新しい診断法 : Dダイマー, TAT, PIC(シンポジウム DIC-診断・治療の最近の動向, 第457回新潟医学会)
佐藤, 正之
131982
DIC
D-D
TAT
PIC
血管内凝固症候群
Dダイマー
トロンビン・アンチトロンビンIII結合体
プラスミン・α_2 プラスミンインヒビター結合体
86 samples which were collected from 41 patients were analyzed for D-dimer (D-D), thrombin/antithrombin III complex (TAT) and plasmin/α_2 plasmin inhibitor complex (PIC). In those patients 53 had established DIC, 19 had most probable DIC, 14 had probable DIC. All those patients were divided into following groups : Group A : established DIC. Group B : most probable DIC. C : probable DIC. The normal value was taken as D-D (<1μg/ml), TAT (1.71±0.71μg/l) and PIC (0.4±0.37μg/ml). In Group A, D-D (16.5±26.2μg/ml, TAT (29.5±20.7μg/l) and PIC (7.2±6.1μg/ml) were elevated significantly. These results suggest significant hypercoagulable and accelerated fibrinolysis state. All the 3 groups have shorn positive correlation with antithrombin III, TAT, α_2 plasmin inhibitor, PIC and D-D in patients with acute promyelocytic leukemia. On the other hand, such correlation for above mentioned tests were not observed in patients with other diseases such as malignant tumors. The abnormalites of D-D, TAT and PIC were observed frequently (86~100%) in each group. D-D, TAT and PIC were found to be useful parameters in DIC. Abnormal findings of these parameters in B and C Groups seem to show hypercoagulability and fibrinolysis even though fibrinogen and platelet count were found to be normal in these groups.
departmental bulletin paper
新潟医学会
1991-02
application/pdf
新潟医学会雑誌
2
105
75
84
新潟医学会雑誌
AN00182415
00290440
https://niigata-u.repo.nii.ac.jp/record/21630/files/105(2)_75-84.pdf
jpn