2024-03-28T13:10:19Z
https://niigata-u.repo.nii.ac.jp/oai
oai:niigata-u.repo.nii.ac.jp:00018853
2022-12-15T03:49:54Z
453:456
471:537:538:1143
Indication of Low Protein Diet and Renal Effects of Different Types of Protein (Recent Advances in Research and Treatment of Diabetes Mellitus)
6)低蛋白食の適応と食事性蛋白質の扱い(シンポジウム 糖尿病研究の進歩と治療, 第498回新潟医学会)
6)低蛋白食の適応と食事性蛋白質の扱い(シンポジウム 糖尿病研究の進歩と治療, 第498回新潟医学会)
中村, 宏志
117698
伊藤, 正毅
117699
柴田, 昭
117700
low protein diet
renal function
glomerular hyperfiltration
albuminuria
prostaglandins
低蛋白食
腎機能
糸球体過剰濾過
アルブミン尿
プロスタグランディン
Previously, it has been reported that a low protein diet prevents the progression of diabetic nephropathy. Low protein alimentation can reduce proteinuria in patients with moderate diabetic nephropathy (serum creatinine ≦ 2.0 mg/dl). However, dietary protein restriction may cause muscle wasting or malnutrition. In a previous report, we examined the influence of proteins from different sources on renal function in healthy volunteers and diabetic patients. Our study showed that ingestion of egg white, cheese or cooked soybean protein did not affect GFR or AER (albumin excretion rate). GFR rose significantly and AER did not change after ingestion of tuna fish. Either GFR or AER rose after ingestion of cooked pork or beef. Urinary 6-keto-PGF_1α excetion increased after ingestion of pork, beef or tuna fish. Urinary TXB_2 excretion increased after pork or beef loading. Our findings suggest that certain kinds of protein can be excepted from dietary portein restriction. Our study involved only acute loading, and prolonged clinical study is necessary to evaluate this possibility and safety.
departmental bulletin paper
新潟医学会
1994-12
application/pdf
新潟医学会雑誌
12
108
897
901
新潟医学会雑誌
AN00182415
00290440
https://niigata-u.repo.nii.ac.jp/record/18853/files/108(12)_897-901.pdf
jpn