2024-03-28T19:32:57Z
https://niigata-u.repo.nii.ac.jp/oai
oai:niigata-u.repo.nii.ac.jp:00014506
2022-12-15T03:46:30Z
453:456
471:537:538:1068
Autonomic Nervous Function in Panic Disorder
パニック障害の自律神経機能
パニック障害の自律神経機能
塩入, 俊樹
93809
細木, 俊宏
93810
小嶋, 麻紀
93811
染矢, 俊幸
93812
板東, 武彦
93813
autonomic nervous function
papillary light reflex
cardiovascular reflex
panic disorder
自律神経神経機能
瞳孔対光反射
血圧反射
パニック障害
In 1980 panic disorder (PD) appeared in the Diagnostic and Statistical Manual of Mental Disorders, 3rd edition(DSM-III)as an anxiety disorder. Patients with PD experience panic attacks characterized by episodes of intense anxiety, shortness of breath, tightness of chest, heart pounding, sweating, dizziness, tremulousness, and other autonomic symptoms. Both sympathetic and parasympathetic system dysfunctions have been implicated in the pathophysiology of panic attack. In the present study, we measured papillary light and cardiovascular reflexes to examine autonomic nervous function in 8 PD patients and 8 age and sex-matched normal control subjects. To our knowledge, using these new methods to evaluate autonomic nervous functions is a first trial in PD. These measurements were done before and after audiovisual stimulation, which was looking at video-images with vivid sound effects on a tangent screen with the distance of 2 m in the dark room(10 lux)for 15 min. In PD patients group, anxious severity (Sheehan’s Anxiety Scale) was relevant to the delay of cardiovascular reflex and the increased variability of papillary diameter by the audiovisual stimulation. Although this study is preliminary, these results suggest the dysfunction of autonomic nervous function in PD and the new available methods for autonomic nervous function.
departmental bulletin paper
新潟医学会
2001-12
application/pdf
新潟医学会雑誌
12
115
627
631
新潟医学会雑誌
AN00182415
00290440
https://niigata-u.repo.nii.ac.jp/record/14506/files/115(12)_627-631.pdf
jpn