2024-10-16T08:25:05Z
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2022-12-15T03:39:58Z
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471:537:568:650
Histopathological Differentiation of Endometrial Adenomatous Hyperplasia from a Well Differentiated Type of Endometrial Adenocarcinoma by Statistical Methods
Histopathological Differentiation of Endometrial Adenomatous Hyperplasia from a Well Differentiated Type of Endometrial Adenocarcinoma by Statistical Methods
Ikarashi, Toshihiko
53838
Sudo, Norihito
53839
Kato, Masami
53840
Hirasawa, Hirobumi
53841
Ishii, Miwako
53842
Kaneko, Hiroshi
53843
This histopathological analysis was statistically performed between specimens of endometrial adenomatous hyperplasia (aH) regarded as a benign proliferative lesion and those of a well-differentiated type of endometrial adenocarcinoma (wC) with low-grade atypiam. Among the examined statistical indices of this histological atypism, the index of glandular area per unit area (IGA), the index of cellular area per unit area (lCA), and the index of gland-in-gland configuration per unit area (lGG) were statistically significant at 0.001, 0.001, and 0.02 levels (t-test), respectively. The multivariate statistical analysis with these reliable indices led the following quadratic discriminant functions: Q(x) = 0.01227x_1^2 - 0.07634x_2^2 - 0.45338x_3^2 -0.11596x_1x_2 ＋0.42307x_2x_3 ＋0.11860x_3x_1＋2.08872x_1 ＋8.90431x_2 -16.82170x_3 -160.49600 (corrective discriminating rate of the aH and the wC : 0.857 and 1.000, respectively), Q'(x) = 0.03324x_1^2 -0.07129x_2^2 -0.02868x_4^2 -0.11888x_1x_2 ＋0.06813x_2x_4 ＋0.03027x_4x_1 -1.20861x_1 ＋6.62168x_2 - 0.98273x_4- 35.40290 (corrective discrimination of the aH and the wC: 1.000 and 1.000, respectively) (x_1 =IGA, x_2=ICA, x_3 =IGG, x_4=age). The multivariate statistical analysis of histopathology is valuable for the differentiation of the wC from the aH.
departmental bulletin paper
Niigata University School of Medicine
1989-06
application/pdf
Acta medica et biologica
1
37
51
54
Acta medica et biologica
AA00508361
05677734
https://niigata-u.repo.nii.ac.jp/record/6656/files/37(1)_51-54.pdf
http://hdl.handle.net/10191/33537
https://niigata-u.repo.nii.ac.jp/records/6656
eng