2023-03-23T11:16:21Z
https://niigata-u.repo.nii.ac.jp/oai
oai:niigata-u.repo.nii.ac.jp:00006642
2022-12-15T03:39:56Z
453:456
471:537:568:648
Histopathological Statistical Discrimination Between Well Differentiated Type of Endometrial Adenocarcinoma and Endometrial Adenomatous Hyperplasia
Histopathological Statistical Discrimination Between Well Differentiated Type of Endometrial Adenocarcinoma and Endometrial Adenomatous Hyperplasia
Ikarashi, Toshihiko
53787
Sudo, Norihito
53788
Kato, Masami
53789
Hirasawa, Hirobumi
53790
Ishii, Miwako
53791
Yasuda, Masahiro
53792
Higashino, Masahiko
53793
The histopathological distinction was statistically examined between an endometrial adenomatous hyperplasia (aH) and a well differentiated type of invasive endometrial adenocarcinoma (wC). The significant morphometric indices were disclosed as follows: (1) indices related to a structural atypism, based on the index of glandular area per unit area (IGA), the index of cellular area per unit area (ICA), and the index of gland-in-gland configuration per unit area (IGG), which were higher in the wC with the significant levels of 0.001, 0.001, and 0.02, respectively (t-test); (2) indices related to a cellular atypism, being made up of the mean nuclear long axial diameter (NLAD), the mean nuclear short axial diameter (NSAD), the mean nuclear area (NA), and the mean nucleolar maximal diameter (nMD), which were larger in the wC with the statistical significances of 0.1, 0.02, 0.05, and 0.05, respectively (t-test); and (3) the mean age of the wC was older than that of the aH with the significance of 0.001 (t-test). Furthermore, the multivariate analysis with the use of these reliable indices led five perfect linear discriminants. It is concluded that the multivariate analysis is valuable for the histopathological distinction between the wC and the aH.
departmental bulletin paper
Niigata University School of Medicine
1989-12
application/pdf
Acta medica et biologica
3-4
37
129
133
Acta medica et biologica
AA00508361
05677734
https://niigata-u.repo.nii.ac.jp/record/6642/files/37(3-4)_129-133.pdf
eng