2024-03-29T01:09:47Z
https://niigata-u.repo.nii.ac.jp/oai
oai:niigata-u.repo.nii.ac.jp:00006482
2022-12-15T03:39:46Z
453:456
471:537:568:624
Bone Chondroblastoma : An Immunohistochemical and Ultrastructural Study
Bone Chondroblastoma : An Immunohistochemical and Ultrastructural Study
Hotta, Tetsuo
53134
Ogose, Akira
53135
Motoyama, Teiichi
53136
Emura, Iwao
53137
Watanabe, Hidenobu
53138
Takahashi, Hideaki
53139
To elucidate the histogenesis of chondroblastoma, we examined seven cases of chondroblastoma immunohistochemically and ultrastructurally. Immunohistochemically, the majority of mononuclear tumor cells were positive for S-100 protein, but far fewer were Type II collagen-positive mononuclear tumor cells. This immunohistochemical pattern was similar to that of embryonal cartilage cells. Moreover, the ultrastructural features of mononuclear tumor cells closely resembled those of embryonal cartilage cells. Osteoclast-like multinucleate giant cells were confirmed to be histiocytic in nature and a reactive element. Our findings suggest that chondroblastoma develops from the remnant of embryonal cartilage.
departmental bulletin paper
Niigata University School of Medicine
1995-03
application/pdf
Acta medica et biologica
1
43
47
52
Acta medica et biologica
AA00508361
05677734
https://niigata-u.repo.nii.ac.jp/record/6482/files/43(1)_47-52.pdf
eng