2024-03-28T22:12:28Z
https://niigata-u.repo.nii.ac.jp/oai
oai:niigata-u.repo.nii.ac.jp:00006453
2022-12-15T03:39:45Z
453:456
471:537:568:621
Renal Lesions in Multiple Myeloma and Related Disorders
Renal Lesions in Multiple Myeloma and Related Disorders
Morita, Takashi
53008
multiple myeloma
cast nephropathy
amyloidosis
light chain deposition disease
Fanconi syndrome
Crow-Fukase syndrome
In addition to the so-called myeloma kidney, various types of renal lesions, apparently relating to intrinsic properties of abnormal immunoglobulin products, have been recognized in multiple myeloma and related disorders. Heavy chain deposition disease and heavy-chain-associated amyloidosis are recent newcomers of this group. Recognition of morphological features of these lesions is important, since renal manifestations occur often in the absence of overt manifestations of multiple myeloma or other plasma cell dyscrasias. Demonstration of an abnormally predominant deposition of one light chain by immunofluorescence study using antikappa and lambda light chain antisera in addition to routine heavy chain staining has been crucial in diagnosing some of these monoclonal light chain-related diseases.
departmental bulletin paper
Niigata University School of Medicine
1995-12
application/pdf
Acta medica et biologica
4
43
173
196
Acta medica et biologica
AA00508361
05677734
https://niigata-u.repo.nii.ac.jp/record/6453/files/43(4)_173-196.pdf
eng