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2022-12-15T03:39:43Z
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Influence of Blood Pressure Level on the Suppression of Proteinuria by Dipyridamole in Diabetic Patients with Nephropathy
Influence of Blood Pressure Level on the Suppression of Proteinuria by Dipyridamole in Diabetic Patients with Nephropathy
Nakamura, Hiroshi
52872
Ito, Seiki
52873
Katagiri, Takashi
52874
Nakagawa, Osamu
52875
Tani, Nagayuki
52876
Shibata, Akira
52877
diabetic nephropathy
proteinuria
dipyridamole
anti-hypertensive therapy
To study the influence of blood pressure on the anti-proteinuric effect of dipyridamole, 14 diabetic patients with proteinuria were divided into two groups: Group A (n=7) in which the mean blood pressure was always >100 mmHg, and Group B (n=7) in which the mean blood pressure might be > 100 mmHg. During the observation period, protein excretions and serum creatinine (Cr) were examined every six months. In Group A, the urinary protein excretion increased during the control period and decreased during dipyridamole therapy. In Group B, the urinary protein excretion increased both during the control period and dipyridamole therapy. △1/Cr was lowered in Group A, but changed rather dramatically in Group B by dipyridamole therapy. We conclude that the anti-proteinuric effect of dipyridamole was achieved in patients with a mean blood pressure of < 100 mmHg.
departmental bulletin paper
Niigata University School of Medicine
1996-09
application/pdf
Acta medica et biologica
3
44
153
156
Acta medica et biologica
AA00508361
05677734
https://niigata-u.repo.nii.ac.jp/record/6429/files/44(3)_153-156.pdf
eng