2024-03-29T13:35:18Z
https://niigata-u.repo.nii.ac.jp/oai
oai:niigata-u.repo.nii.ac.jp:00005827
2022-12-15T03:39:03Z
453:455
471:561:562
上顎洞底挙上術における培養骨膜細胞の臨床的有効性の高解像度三次元的CT分析
High-Resolution Three-Dimensional Computed Tomography Analysis of the Clinical Efficacy of Cultured Autogenous Periosteal Cells in Sinus Lift Bone Grafting
High-Resolution Three-Dimensional Computed Tomography Analysis of the Clinical Efficacy of Cultured Autogenous Periosteal Cells in Sinus Lift Bone Grafting
Ogawa, Shin
50941
cultured autogenous periosteal cell
sinus lift bone augmentation
three-dimensional computed tomography
新潟大学
博士(学術)
Background and Purpose: Sinus lift (SL) using cultured autogenous periosteal cells (CAPCs) combined with autogenous bone and platelet-rich plasma (PRP) was performed to evaluate the effect of cell administration on bone regeneration, by using high-resolution three-dimensional computed tomography (CT).Materials andMethods: SL with autogenous bone and PRP plus CAPC [CAPC(+)SL] was performed in 23 patients. A piece of periosteum taken from the mandible was cultured in M199 medium with 10% fetal bovine serum (FBS) for 6 weeks. As control, 16 patients received SL with autogenous bone and PRP [CAPC(−)SL]. Three-dimensional CT imaging was performed before and 4 months and 1 year after SL, and stratification was performed based on CT numbers (HUs) corresponding to soft tissue and cancellous or cortical bone. Results: The augmented bone in CAPC(+)SL revealed an increase in HUs corresponding to cancellous bone as well as a decrease in HUs corresponding to grafted cortical bone. In addition,HUs corresponding to cancellous bone in the graft bed were increased in CAPC(+)SL but were decreased in CAPC(−)SL. Insertion torque during implant placement was significantly higher in CAPC(+)SL. Conclusion: By promoting bone anabolic activity both in augmented bone and graft bed, CAPCs are expected to aid primary fixation and osseointegration of implants in clinical applications.
学位の種類: 博士(学術). 報告番号: 乙第2203号. 学位記番号: 新大博(学)乙第74号. 学位授与年月日: 平成28年9月20日
Clin Implant Dent Relat Res. 2016 Aug;18(4):707-16
新大博(学)乙第74号
thesis
新潟大学
2016-09-20
2016-09-20
application/pdf
application/pdf
13101乙第2203号
https://niigata-u.repo.nii.ac.jp/record/5827/files/h28nio74.pdf
https://niigata-u.repo.nii.ac.jp/record/5827/files/h28nio74_a.pdf
eng
info:doi/10.1111/cid.12356
© 2015 Wiley Periodicals, Inc