2026-03-15T17:46:42Z https://niigata-u.repo.nii.ac.jp/oai

oai:niigata-u.repo.nii.ac.jp:00009706 2022-12-15T03:43:40Z 453:456 471:537:538:943

NIRS・脳波同時記録による運動関連脳皮質活動の研究 NIRS・脳波同時記録による運動関連脳皮質活動の研究 Movement-related Cortical Activation: Simultaneous Monitoring of Near-infrared Spectroscopy Signals and Movement-related Cortical Potentials 佐藤, 洋輔 福多, 真史 大石, 誠 藤井, 幸彦 Near-infrared spectroscopy movement-related cortical potentials event-related potential hand motor task motor control This study was designed to evaluate hemodynamic and electrophysiological responses in the motor cortex to voluntary finger pinching movements in healthy humans. Near-infrared spectroscopy (NIRS) signals and movement-related cortical potentials (MRCP) were recorded simultaneously. Three healthy right-handed subjects performed 100 trials of voluntary right thumb- index finger pinching with approximate 10 s intervals at their own pace. Throughout the session, 48 regions of the bilateral motor cortex were assessed by NIRS, while MRCPs were simultaneously monitored at Fz, Cz, C3, and C4 of the 10-20 International System. An electromyogram (EMG) was also recorded from the right first dorsal interosseus muscle. MRCPs, which were clearly detected in all subjects, started 1585±13 ms before EMG onset and peaked 110±13 ms after EMG onset. NIRS data showed bilateral prefrontal cortical (PFC) and bilateral dorsal premotor cortical (dPMC) activation during the preparation phase (PFC: peaking at 0.5±0.1 s before EMG onset, dPMC: peaking at 0.5±0.1 s before EMG onset). Following the cortical activation, the hand area of the sensorimotor cortex, which was dominantly activated on the left, peaked at 3.7 ± 0.2 s after EMG onset. These results indicate that our technique allowed detailed study of the motor control system. 新潟医学会 2012-05 jpn departmental bulletin paper http://hdl.handle.net/10191/31494 https://niigata-u.repo.nii.ac.jp/records/9706 AN00182415 00290440 新潟医学会雑誌 新潟医学会雑誌 126 5 256 264 https://niigata-u.repo.nii.ac.jp/record/9706/files/126(5)_256-264.pdf application/pdf 2.1 MB 2019-08-06