2024-03-29T15:01:53Z
https://niigata-u.repo.nii.ac.jp/oai
oai:niigata-u.repo.nii.ac.jp:02000314
2022-12-15T04:28:02Z
453:455
471:561:562
Skipping breakfast, late-night eating and current smoking are associated with medication adherence in Japanese patients with diabetes
朝食欠食、就寝前夕食、喫煙は日本人糖尿病患者の服薬アドヒアランスに関連する
Yaguchi, Yuta
矢口, 雄大
open access
【○!C】 2020 Primary Care Diabetes Europe. Published by Elsevier Ltd. All rights reserved.
Oral hypoglycemic agent
Medication adherence
Clinical epidemiology
Aims: Little is known about the relationship between medication adherence for oral hypoglycemic agents (OHAs) and glycemic control after adjusting healthy adherer effect in large scale study. Thus, adjusting for health-related behaviors, we investigated the clinical variables associated with medication adherence and the relationship between medication adherence and glycemic control using a large claims database. Methods: Analyzed were 8805 patients with diabetes whose medication records for OHA were available for at least 1 year. Medication adherence was evaluated by the proportion of days covered (PDC). Multivariate logistic regression model was used to identify clinical variables significantly associated with non-adherence. Multiple regression analysis evaluated the relationship between PDC and HbA1c after adjusting for health-related behaviors. Results: Mean PDC was 80.1% and 32.8% of patients were non-adherence. Logistic analysis indicated that older age and taking concomitant medications were significantly associated with adherence while skipping breakfast (odds ratio 0.66 [95% CI 0.57–0.76]), late-night eating (0.86 [0.75–0.98]), and current smoking (0.89 [0.80–0.99]) were significantly associated with non-adherence. Conclusions: Skipping breakfast, late-night eating and current smoking were significantly associated with medication adherence, suggesting that clinicians pay attention to those health-related behaviors to achieve good medication adherence.
Primary Care Diabetes. 2020, 14(6), 753-759.
新大院博(医)第1009号
eng
doctoral thesis
http://hdl.handle.net/10191/0002000314
https://niigata-u.repo.nii.ac.jp/records/2000314
https://doi.org/10.1016/j.pcd.2020.05.002
甲第4855号
博士(医学)
2021-03-23
13101
新潟大学
Niigata University
https://niigata-u.repo.nii.ac.jp/record/2000314/files/r2nmk1009.pdf
application/pdf
985KB
2022-04-04
https://niigata-u.repo.nii.ac.jp/record/2000314/files/r2nmk1009_a.pdf
application/pdf
544KB
2022-04-04