2024-03-29T12:04:44Z
https://niigata-u.repo.nii.ac.jp/oai
oai:niigata-u.repo.nii.ac.jp:00021391
2022-12-15T03:51:57Z
453:456
471:537:538:1185
十二指腸乳頭部のカルチノイド腫瘍と内分泌細胞微小胞巣に関する形態計測・免疫組織化学的研究
十二指腸乳頭部のカルチノイド腫瘍と内分泌細胞微小胞巣に関する形態計測・免疫組織化学的研究
Carcinoid Tumor and Endocrine Cell Micronests of the Duodenal Papillae : Morphometrical and Immunohistochemical Study
野田, 裕
duodenal papilla
duodenal minor papilla
carcinoid tumor
endocrine cell micronest
十二指腸乳頭部
十二指腸副乳頭
カルチノイド腫瘍
内分泌細胞微小胞巣(ECM)
Morphometrical and immunohistochemical characteristics of carcinoid tumor and endocrine cell micronest [ECM] of the minor and major duodenal papillae were studied. For this purpose, consecutive 90 autopsy and 134 surgical materials were examined by mirror-image paraffin-embedded tissues. ECM was frequently found in these areas, and its aggregation-pattern was classified into four types^2 Nodular type (Type 1) (2/196 in the minor papilla, 1/165 in the major papilla), Scattered type (Type 2) (45/196, 8/165), Orifice type (Type 3) (8/196, 0/165) and Islet-like type (Type 4) (18/196, 0/165). The endocrine cells of these ECMs were usually immunoreactive only for somatostatin and/or pancreatic polypeptide except for those of type 4. The type 4 was regarded to be atrophic or regenerating islet of Langerhans, and was finally excluded from ECM. By a tentative criteria, distinct carcinoid (type 1), neoplastic ECMs, and non-neoplastic ECMs were found in 1.0%, 8.2% and 16.8% of 196 cases in the minor papilla, and 0.6%, 1.2% and 3.6% of 165 cases in the major papilla respectively. In the duodenal papillae, especially in the minor duodenal papilla, carcinoid tumor and ECM seem to be present more frequently than generally thought. Difference between each type of ECM/carcinoid tumor was histologically analysed, and characteristics of each type was finally clarified.
新潟医学会
1991-06
jpn
departmental bulletin paper
http://hdl.handle.net/10191/38893
https://niigata-u.repo.nii.ac.jp/records/21391
AN00182415
00290440
新潟医学会雑誌
新潟医学会雑誌
105
6
410
420
https://niigata-u.repo.nii.ac.jp/record/21391/files/105(6)_410-420.pdf
application/pdf
3.6 MB
2019-08-16