2024-03-29T14:50:23Z
https://niigata-u.repo.nii.ac.jp/oai
oai:niigata-u.repo.nii.ac.jp:00021051
2022-12-15T03:51:39Z
453:456
471:537:538:1175
N-Isopropyl-p-[^<123>I]Iodoamphetamine(IMP)SPECTにおけるDelayed Fill-in Phenomenon(いわゆる再分布現象)の意義
N-Isopropyl-p-[^<123>I]Iodoamphetamine(IMP)SPECTにおけるDelayed Fill-in Phenomenon(いわゆる再分布現象)の意義
Regional Cerebral Blood Flow Measured With N-Isopropyl-p-[^<123>I] Iodoamphetamine and its Delayed Fill-in Phenomenon (Redistribution) in Cerebro-vascular Diseases
小田野, 行男
^<123>I-IMP
SPECT
Redistribution
Ischemic disease
局所脳血流測定
Single photon emission computed tomography (SPECT) using N-isopropyl-p-[^<123>I] iodoamphetamine (IMP) studies were performed on 17 patients (23-77 yrs) with cerebrovascular diseases and 10 age-matched normal controls. Regional cerebral blood flow (rCBF) was quantitatively measured by a microsphere model, and a relationship between rCBF in ischemic lesions and the redistribution phenomenon on delayed SPECT image was analyzed. Supratentorial mean CBF and a gray-to-white matter ratio of normal subjects were 52.7±5.0ml/100g/min and 2.34, respectively. Low activity areas of ischemic lesions on early IMP SPECT were classified into two abnormal zones, an infarct area and a peri-infarct area. These regions were characterized by rCBF averaging 9~20ml/100g/min, and 25~40ml/100g/min, respectively. The redistribution, which was hardly observed in the infarct area, was markedly enhanced in the peri-infarct area. The data indicates that the redistribution depends on maintenance of a minimal blood flow that would sustain cellular function.
新潟医学会
1992-04
jpn
departmental bulletin paper
http://hdl.handle.net/10191/39648
https://niigata-u.repo.nii.ac.jp/records/21051
AN00182415
00290440
新潟医学会雑誌
新潟医学会雑誌
106
4
243
247
https://niigata-u.repo.nii.ac.jp/record/21051/files/106(04)_243-247.pdf
application/pdf
1.0 MB
2019-08-16