2023-09-27T07:25:08Z
https://niigata-u.repo.nii.ac.jp/oai
oai:niigata-u.repo.nii.ac.jp:00006656
2022-12-15T03:39:58Z
453:456
471:537:568:650
Histopathological Differentiation of Endometrial Adenomatous Hyperplasia from a Well Differentiated Type of Endometrial Adenocarcinoma by Statistical Methods
Histopathological Differentiation of Endometrial Adenomatous Hyperplasia from a Well Differentiated Type of Endometrial Adenocarcinoma by Statistical Methods
Ikarashi, Toshihiko
Sudo, Norihito
Kato, Masami
Hirasawa, Hirobumi
Ishii, Miwako
Kaneko, Hiroshi
This histopathological analysis was statistically performed between specimens of endometrial adenomatous hyperplasia (aH) regarded as a benign proliferative lesion and those of a well-differentiated type of endometrial adenocarcinoma (wC) with low-grade atypiam. Among the examined statistical indices of this histological atypism, the index of glandular area per unit area (IGA), the index of cellular area per unit area (lCA), and the index of gland-in-gland configuration per unit area (lGG) were statistically significant at 0.001, 0.001, and 0.02 levels (t-test), respectively. The multivariate statistical analysis with these reliable indices led the following quadratic discriminant functions: Q(x) = 0.01227x_1^2 - 0.07634x_2^2 - 0.45338x_3^2 -0.11596x_1x_2 ＋0.42307x_2x_3 ＋0.11860x_3x_1＋2.08872x_1 ＋8.90431x_2 -16.82170x_3 -160.49600 (corrective discriminating rate of the aH and the wC : 0.857 and 1.000, respectively), Q'(x) = 0.03324x_1^2 -0.07129x_2^2 -0.02868x_4^2 -0.11888x_1x_2 ＋0.06813x_2x_4 ＋0.03027x_4x_1 -1.20861x_1 ＋6.62168x_2 - 0.98273x_4- 35.40290 (corrective discrimination of the aH and the wC: 1.000 and 1.000, respectively) (x_1 =IGA, x_2=ICA, x_3 =IGG, x_4=age). The multivariate statistical analysis of histopathology is valuable for the differentiation of the wC from the aH.
Niigata University School of Medicine
1989-06
eng
departmental bulletin paper
http://hdl.handle.net/10191/33537
https://niigata-u.repo.nii.ac.jp/records/6656
AA00508361
05677734
Acta medica et biologica
Acta medica et biologica
37
1
51
54
https://niigata-u.repo.nii.ac.jp/record/6656/files/37(1)_51-54.pdf
application/pdf
592.1 kB
2019-08-06