2024-03-29T01:06:08Z
https://niigata-u.repo.nii.ac.jp/oai
oai:niigata-u.repo.nii.ac.jp:00006644
2022-12-15T04:30:43Z
453:456
471:537:568:649
β_2-Microglobulin-Related Amyloidosis in Chronic Hemodialysis Patients
β_2-Microglobulin-Related Amyloidosis in Chronic Hemodialysis Patients
Gejyo, Fumitake
Maruyama, Hiroki
Arakawa, Masaaki
Amyloidosis, containing β_2-microglobulin (β_2-M), and osteoarthropathy are frequent complications of long-term hemodialysis, but the mechanism of its development is not completely known as yet. β_2-M is an amyloid protein, though other factors including calcium are greatly involved in the development of this disease. Regarding the treatment of dialysis amyloidosis, there has been progress in the development of a β_2-M adsorption column and the successful elimination of β_2-M from blood. Extensive studies should be performed to investigate the effect of antioxidants. This paper first reviews the current concepts concerning dialysis amyloidosis, secondly discusses the factors involved in the pathogenesis and finally, attempts to outline new perspectives of treatment for the disease.
Niigata University School of Medicine
1989-09
eng
departmental bulletin paper
http://hdl.handle.net/10191/33538
https://niigata-u.repo.nii.ac.jp/records/6644
AA00508361
05677734
Acta medica et biologica
Acta medica et biologica
37
2
55
61
https://niigata-u.repo.nii.ac.jp/record/6644/files/37(2)_55-61.pdf
application/pdf
1.8 MB
2019-08-06