2024-03-28T19:25:37Z
https://niigata-u.repo.nii.ac.jp/oai
oai:niigata-u.repo.nii.ac.jp:00006495
2022-12-15T03:39:50Z
453:456
471:537:568:626
The Usefulness of Routine Liver Function Tests in the Discrimination of Extrahepatic Biliary Atresia from Physiologic Jaundice in the Early Neonatal Period
The Usefulness of Routine Liver Function Tests in the Discrimination of Extrahepatic Biliary Atresia from Physiologic Jaundice in the Early Neonatal Period
Yamagiwa, Iwao
Iwafuchi, Makoto
Washio, Masahiko
Results of routine liver function tests performed prior to Kasai's operation within 12 weeks after birth in 50 patients with extrahepatic biliary atresia during 1981 to 1992 were retrospectively analyzed. Thirty neonatal patients without cholestatic disease served as the control group. Total bilirubin, direct bilirubin and gamma-glutamyl transpeptidase levels were significantly different between the extrahepatic biliary atresia and control groups within I week after birth (16.1±3.2 mg/dl vs. 11.6±4.7 mg/dl, 4.6±2.6 mg/dl vs. 0.6±0.2 mg/dl, 701±228 IU/1 vs. 56±21IU/1 respectively). Conversely, no differences were observed between them in the levels of aminotransferases within 2 weeks after birth. These data suggest that no hepatocellular damage occurs at least 2 weeks after birth in extrahepatic biliary atresia, and that the determination of bilirubin and gamma-glutamyl transpeptidase levels within 1 week after birth enable us to distinguish patients with extrahepatic biliary atresia from physiologic jaundice during this period.
Niigata University School of Medicine
1994-09
eng
departmental bulletin paper
http://hdl.handle.net/10191/33247
https://niigata-u.repo.nii.ac.jp/records/6495
AA00508361
05677734
Acta medica et biologica
Acta medica et biologica
42
3
109
113
https://niigata-u.repo.nii.ac.jp/record/6495/files/42(3)_109-113.pdf
application/pdf
537.7 kB
2019-08-06