2024-03-28T15:10:12Z
https://niigata-u.repo.nii.ac.jp/oai
oai:niigata-u.repo.nii.ac.jp:00006336
2022-12-15T03:39:39Z
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471:537:568:604
Selective Increments of Superior Mesenteric Artery Blood Flow by Dopamine Administration in the Pig
Selective Increments of Superior Mesenteric Artery Blood Flow by Dopamine Administration in the Pig
CUI, Xing
SUDA, Takeyasu
SAKAGUCHI, Takeo
AONO, Takashi
ISHIZUKA, Dai
SASAKI, Masataka
HATAKEYAMA, Katsuyoshi
dopamine
blood flow
mesenteric circulation
intestine
pig
Circulatory responses in major branches of the superior mesenteric artery were examined after dopamine (DA) administration into the jugular vein in anesthetized pigs. DA at 10 μg/kg/min for 2 min produced an increase in superior mesenteric arterial blood flow (SMAF) and jejunal arterial blood flow (JAF) without any change in right colic arterial blood flow (RCAF), ileocolic arterial blood flow (ICAF) or systemic arterial blood pressure (SAP). The SMAF and JAF response tended to be dose dependent when the does of DA ranged from 5 to 20 μg/kg/min. A significant increase in RCAF was induced when the dose of DA was increased to 20 μg/kg/min, but no change in ICAF was seen. Liver and kidney function scores were unchanged after the DA injection. These findings suggest that DA is active in increasing superior mesenteric arterial blood flow, but the action of DA is differential at the major branch level.
Niigata University School of Medicine
2000-03
eng
departmental bulletin paper
http://hdl.handle.net/10191/1830
https://niigata-u.repo.nii.ac.jp/records/6336
AA00508361
05677734
Acta medica et biologica
Acta medica et biologica
48
1
25
30
https://niigata-u.repo.nii.ac.jp/record/6336/files/KJ00000007242.pdf
application/pdf
6.4 MB
2019-08-06