2024-03-29T11:24:01Z
https://niigata-u.repo.nii.ac.jp/oai
oai:niigata-u.repo.nii.ac.jp:00002603
2022-12-15T03:35:44Z
176:488:489
453:454
A formal method for the de-N,N-dialkylation of Sommelet-Hauser rearrangement products
Tayama, Eiji
Sato, Ryota
Takedachi, Keisuke
Iwamoto, Hajime
Hasegawa, Eietsu
Amino acid
Ammonium ylide
De-alkylation
Rearrangement
Substitution
Selective amine de-alkylation enables the conversion of Sommelet–Hauser rearrangement products into 2-aryl-2-bromoacetic acid derivatives. These compounds are valuable synthetic intermediates in the synthesis of α-aryl-α-amino or α-aryl-β-amino acid derivatives. The method presented herein is a formal de-N,N-dialkylation of Sommelet–Hauser rearrangement products.
Elsevier
2012-06
eng
journal article
http://hdl.handle.net/10191/27226
https://niigata-u.repo.nii.ac.jp/records/2603
info:doi/10.1016/j.tet.2012.04.015
AA00861787
00404020
Tetrahedron
Tetrahedron
68
24
4710
4718
https://niigata-u.repo.nii.ac.jp/record/2603/files/1514A.pdf
application/pdf
328.7 kB
2019-07-29