2024-03-28T14:54:50Z
https://niigata-u.repo.nii.ac.jp/oai
oai:niigata-u.repo.nii.ac.jp:00002156
2022-12-15T04:14:53Z
453:454
482:483:484
CD56+, NKp46+ cell line (MZ93) expressing T-cell and myeloid antigens
Hashimoto, Shigeo
Toba, Ken
Tsuchiyama, Junjiro
Abe, Takashi
Yano, Toshio
Momoi, Akihito
Okazuka, Kiyoshi
Kanazawa, Naoko
Takahashi, Masuhiro
Aizawa, Yoshifusa
Elsevier Ltd
T
NK cell precursor acute leukemia
cell line
MZ93
CD56
NKp46
chronic myelogeneous leukemia.
The MZ93 cell line, established from a patient with CML, expressed CD4, CD7, GD13, CD25, CD33, CD34, CD56 and NKp46. The additional karyotype abnormality of the Ph-positive leukemia cells in vivo, 6p+, was also observed in the MZ93. The early passages of MZ93 expressed CD3 in the cytoplasm, but the late passages did not. The cells did not express mature NK-markers as expected. The messenger RNAs of CD2 and NKp46 were detected and those of CD3ε and CD3ζ were absent in the cells. Therefore, the cell line has the immunophenotype likely to NK and/or T cell precursor.
Elsevier
2002-03
eng
journal article
VoR
http://hdl.handle.net/10191/1176
https://niigata-u.repo.nii.ac.jp/records/2156
http://doi.org/10.1016/s0145-2126(01)00115-1
AA00716755
0145-2126
Leukemia Research
Leukemia Research
26
3
289
295
https://niigata-u.repo.nii.ac.jp/record/2156/files/24_0018.pdf
application/pdf
390.5 kB
2019-07-29