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oai:niigata-u.repo.nii.ac.jp:00001615
2022-12-15T03:34:17Z
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Functional analysis of phenylalanine 365 in hopene synthase, a conserved amino acid in the families of squalene and oxidosqualene cyclases
Functional analysis of phenylalanine 365 in hopene synthase, a conserved amino acid in the families of squalene and oxidosqualene cyclases
Hoshino, Tsutomu
Sato, Tsutomu
Two bicyclic products were accumulated by the mutant F365A, showing the amino acid residue is located close to the transient C-8 carbocation intermediate in the active site cavity; the mutants of F365Y and F365W significantly accelerated the cyclization reaction at low temperatures.
Royal Society of Chemistry
1999-11
eng
journal article
http://hdl.handle.net/10191/25028
https://niigata-u.repo.nii.ac.jp/records/1615
info:doi/10.1039/A905559B
AA11071130
13597345
Chemical communications
Chemical communications
1999
19
2005
2006
https://niigata-u.repo.nii.ac.jp/record/1615/files/1999_2005-2006.pdf
application/pdf
70.8 kB
2019-07-29