2024-03-28T15:59:01Z
https://niigata-u.repo.nii.ac.jp/oai
oai:niigata-u.repo.nii.ac.jp:00001614
2022-12-15T03:34:17Z
453:454
485:486:487
Functional analysis of Phe605, a conserved aromatic amino acid in squalene–hopene cyclases
Functional analysis of Phe605, a conserved aromatic amino acid in squalene–hopene cyclases
Hoshino, Tsutomu
Kouda, Masanori
Abe, Takamasa
Sato, Tsutomu
Incubation of squalene with the site-directed mutant F605A of squalene–hopene cyclase from Alicyclobacillus acidocaldarius yielded many triterpenes consisting of the 6/6/5-fused tri-, 6/6/6/5-fused tetra-, and 6/6/6/6/5-fused pentacyclic skeletons, the function of F605 being assignable for facilitating the ring expansion and for stabilizing the hopanyl C22-cation, possibly via cation-π interactions.
Royal Society of Chemistry
2000-07
eng
journal article
http://hdl.handle.net/10191/25029
https://niigata-u.repo.nii.ac.jp/records/1614
info:doi/10.1039/B004129G
AA11071130
13597345
Chemical communications
Chemical communications
2000
16
1485
1486
https://niigata-u.repo.nii.ac.jp/record/1614/files/2000_1485-1486.pdf
application/pdf
509.4 kB
2019-07-29