2024-03-28T09:47:09Z
https://niigata-u.repo.nii.ac.jp/oai
oai:niigata-u.repo.nii.ac.jp:00001611
2022-12-15T03:34:16Z
453:454
485:486:487
Biosynthesis of violacein: a genuine intermediate, protoviolaceinic acid, produced by VioABDE, and insight into VioC function
Biosynthesis of violacein: a genuine intermediate, protoviolaceinic acid, produced by VioABDE, and insight into VioC function
Shinoda, Kouhei
Hasegawa, Takuji
Sato, Hiroaki
Shinozaki, Masaaki
Kuramoto, Hirotomo
Takamiya, Yosuke
Sato, Tsutomu
Nikaidou, Naoki
Watanabe, Takeshi
Hoshino, Tsutomu
A biosynthetic intermediate of violacein produced by the mixed enzymes of VioABDE was elucidated to be 5-(5-hydroxy-1H-indol-3-yl)-3-(1H-indol-3-yl)-1H-pyrrole-2-carboxylic acid, named protoviolaceinic acid, indicating that VioC, responsible for the final biosynthetic step, works to oxygenate at the 2-position of the right side indole ring, and that the oxygenation reaction to form the central pyrrolidone core proceeds in a non-enzymatic fashion.
Royal Society of Chemistry
2007-08
eng
journal article
http://hdl.handle.net/10191/25032
https://niigata-u.repo.nii.ac.jp/records/1611
info:doi/10.1039/B705358D
AA11071130
13597345
Chemical communications
Chemical communications
2007
40
4140
4142
https://niigata-u.repo.nii.ac.jp/record/1611/files/2007_4140-4142.pdf
application/pdf
303.2 kB
2019-07-29