Measurement of Degree of Mixing on Particulate Matters of Three Components using Radionuclides of ^<99m>Tc and ＾<113ｍ>In in Pharmaceutical Dispensing : Studies of Measurement Methods and Applications on Powders
Mixing properties of the pharmaceutical powders were examined by the use of radionuclides of indium-113m and technetium-99m which have short-livies, as double tracer to three components. 1.From the result of experiments, it was shown that the mixing properties of three component preparations were easily estimated by measuring the radioactivity of two components only. 2. Experimental results indicated that the mixing behavir was greatly affected by the physical properties of medicinal powders and granules in the mixed preparations. 3. Experimental results indicated that the mixing properties were greatly affected the physical properties of medicinal excipients and the mixing time in the preparation of mixed drugs with ^<99ｍ>Tc-phenobarbital and ＾<113ｍ>Ｉn-Phenytoin.
テクネチウム99m・インジウム113m併用による三成分系医薬品粉粒体の混合度測定 : 測定法の開発と散剤への応用
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