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Gastric Acid Secretion Controlled by the Oxytocinergic Neuron in the Hypothalamic Paraventricular Nucleus
http://hdl.handle.net/10191/33383
http://hdl.handle.net/10191/33383c6ae93bb-77ba-4752-86a0-8b0a4c09452f
名前 / ファイル | ライセンス | アクション |
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40(3)_89-96.pdf (1.1 MB)
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Item type | 紀要論文 / Departmental Bulletin Paper(1) | |||||
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公開日 | 2015-09-18 | |||||
タイトル | ||||||
タイトル | Gastric Acid Secretion Controlled by the Oxytocinergic Neuron in the Hypothalamic Paraventricular Nucleus | |||||
タイトル | ||||||
言語 | en | |||||
タイトル | Gastric Acid Secretion Controlled by the Oxytocinergic Neuron in the Hypothalamic Paraventricular Nucleus | |||||
言語 | ||||||
言語 | eng | |||||
資源タイプ | ||||||
資源 | http://purl.org/coar/resource_type/c_6501 | |||||
タイプ | departmental bulletin paper | |||||
著者 |
Sakaguchi, Takeo
× Sakaguchi, Takeo |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Morphological studies have revealed neural connections containing oxytocin (OXT) between the hypothalamic paraventricular nucleus (PVN) and medulla oblongata. Electrophysiologically, it has also been shown that there is a functionally specific correlation between the PVN and medullary neurons that are related to the gastric function. Moreover, it was observed that activation of oxytocinergic neurons in the PVN caused by electrical stimulation or OXT application strongly influences gastric acid secretion. The inhibitory response in acid secretion is substantially blocked by vagotomy or by an anticholinergic agent applied onto the medullary gastric neuron and the peripheral site. Since OXT has been shown to be synthesized in the PVN magnocellular nucleus and act locally within the nucleus to control its activity, these findings suggest that the activation of oxytocinergic neurons due to intrinsic OXT within the PVN participates in the control of gastric acid secretion with a change in vagal activity, and that a specific nucleus localized in the medulla oblongata is involved in this system as a relaying mechanism. | |||||
書誌情報 |
Acta medica et biologica en : Acta medica et biologica 巻 40, 号 3, p. 89-96, 発行日 1992-09 |
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出版者 | ||||||
出版者 | Niigata University School of Medicine | |||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 05677734 | |||||
書誌レコードID | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AA00508361 | |||||
著者版フラグ | ||||||
値 | publisher |