WEKO3
アイテム
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Methods: The reactivity of lymphocytes against spouse\u0027s lymphocytes in a mixed lymphocyte culture reaction (MLR) was serially evaluated in married female patients with unexplained recurrent abortion who underwent immunotherapy. Results: Reactivity against the spouse\u0027s lymphocytes significantly decreased after immunotherapy compared with that before therapy (n=19, p\u003c0.01, Wilcoxon test). Reactivity during the first trimester of the new pregnancy was also significantly lower than that before immunotherapy in married female patients with a successful outcome (n=9, p\u003c 0.05, Wilcoxon test). Reactivity in MLR, however, was significantly higher in married female patients who subsequently had repeated spontaneous abortion (n=4, p\u003c0.05, Wilcoxon test). 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MLR Reactivity against Spouse's Lymphocytes : Successful Cases with Unexplained Recurrent Abortion Treated by Immunotherapy with Spouse's Cells
http://hdl.handle.net/10191/33219
http://hdl.handle.net/10191/33219ca9ded92-88ed-4f07-bedc-e060de645496
名前 / ファイル | ライセンス | アクション |
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43(4)_211-216.pdf (572.5 kB)
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Item type | 紀要論文 / Departmental Bulletin Paper(1) | |||||
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公開日 | 2015-08-31 | |||||
タイトル | ||||||
タイトル | MLR Reactivity against Spouse's Lymphocytes : Successful Cases with Unexplained Recurrent Abortion Treated by Immunotherapy with Spouse's Cells | |||||
タイトル | ||||||
言語 | en | |||||
タイトル | MLR Reactivity against Spouse's Lymphocytes : Successful Cases with Unexplained Recurrent Abortion Treated by Immunotherapy with Spouse's Cells | |||||
言語 | ||||||
言語 | eng | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | recurrent abortion | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | immunotherapy | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | MLR | |||||
資源タイプ | ||||||
資源 | http://purl.org/coar/resource_type/c_6501 | |||||
タイプ | departmental bulletin paper | |||||
著者 |
Kazama, Yoshiki
× Kazama, Yoshiki× Takakuwa, Koichi× Tanaka, Kenichi |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Problem: What are the possible underlying mechanisms of immunotherapy for unexplained recurrent abortion using spouse's cells? Methods: The reactivity of lymphocytes against spouse's lymphocytes in a mixed lymphocyte culture reaction (MLR) was serially evaluated in married female patients with unexplained recurrent abortion who underwent immunotherapy. Results: Reactivity against the spouse's lymphocytes significantly decreased after immunotherapy compared with that before therapy (n=19, p<0.01, Wilcoxon test). Reactivity during the first trimester of the new pregnancy was also significantly lower than that before immunotherapy in married female patients with a successful outcome (n=9, p< 0.05, Wilcoxon test). Reactivity in MLR, however, was significantly higher in married female patients who subsequently had repeated spontaneous abortion (n=4, p<0.05, Wilcoxon test). Conclusion: It is suggested that the attenuation of the reactivity against the spouse's lymphocytes might be implicated in the successful pregnancy of patients with unexplained recurrent abortion who underwent the immunotherapy. | |||||
書誌情報 |
Acta medica et biologica en : Acta medica et biologica 巻 43, 号 4, p. 211-216, 発行日 1995-12 |
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出版者 | ||||||
出版者 | Niigata University School of Medicine | |||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 05677734 | |||||
書誌レコードID | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AA00508361 | |||||
著者版フラグ | ||||||
値 | publisher |