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Immunological Effects of Lumin-A, a Fluorescent Antioxidant Drug, on T Cell Subsets in Various Immune Organs of Mice
http://hdl.handle.net/10191/33218
http://hdl.handle.net/10191/332186415a600-1c18-4ff5-bbbc-59bc7ffb9973
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
43(4)_205-209.pdf (557.3 kB)
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| Item type | 紀要論文 / Departmental Bulletin Paper(1) | |||||
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| 公開日 | 2015-08-31 | |||||
| タイトル | ||||||
| タイトル | Immunological Effects of Lumin-A, a Fluorescent Antioxidant Drug, on T Cell Subsets in Various Immune Organs of Mice | |||||
| タイトル | ||||||
| タイトル | Immunological Effects of Lumin-A, a Fluorescent Antioxidant Drug, on T Cell Subsets in Various Immune Organs of Mice | |||||
| 言語 | en | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | lumin-A | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | antioxidant drug | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | extrathymic T cell | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | thymus-derived T cell | |||||
| 資源タイプ | ||||||
| 資源 | http://purl.org/coar/resource_type/c_6501 | |||||
| タイプ | departmental bulletin paper | |||||
| 著者 |
Ohtsuka, Kazuo
× Ohtsuka, Kazuo× Yamamura, Soichiro× Osman, Yasser× Arai, Katsumitsu× Hasegawa, Katsuhiko× Yamagiwa, Satoshi× Nakayama, Mauro× Abo, Toru |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | It is important to determine how fluorescent antioxidant drugs act as immunomodulators. Since a new T-cell population, namely, extrathymic T cells, has recently been identified in the liver and other immune organs, our attention was focused on how one of the above-mentioned drugs (Lumin-A in this study) affects the distribution of extrathymic T cells and thymus-derived T cells in various immune organs. When Lumin-A was administered into mice daily (10 μg/mouse/day) with intraperitoneal or oral route for 3 wks, its unique effect was observed, depending on the routes. Especially, the oral ad libitum administration of Lumin-A induced a prominent induction of thymus-derived T cells, but not extrathymic T cells, in the peripheral immune organs, the spleen and the liver. The present results suggest that a fluorescent antioxidant drug, Lumin-A, has an ability to induce the thymus-derived T cells, i.e., usual T cells for processing foreign antigens, into the periphery. | |||||
| 書誌情報 |
Acta medica et biologica en : Acta medica et biologica 巻 43, 号 4, p. 205-209, 発行日 1995-12 |
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| 出版者 | ||||||
| 出版者 | Niigata University School of Medicine | |||||
| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 05677734 | |||||
| 書誌レコードID | ||||||
| 収録物識別子タイプ | NCID | |||||
| 収録物識別子 | AA00508361 | |||||
| 著者版フラグ | ||||||
| 値 | publisher | |||||
