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  1. 0 資料タイプ別
  2. 03 紀要論文
  1. 250 大学院医歯学総合研究科(医)
  2. 20 紀要
  3. 01 Acta medica et biologica
  4. Vol.53 No.3

Usefulness of the Outpatient Chemotherapy Regimen of S-1 Followed by Weekly Paclitaxel for Far Advanced Gastric Cancer

http://hdl.handle.net/10191/1916
http://hdl.handle.net/10191/1916
9253838c-e086-4606-8650-03635cfa2b7d
名前 / ファイル ライセンス アクション
KJ00004355699.pdf KJ00004355699.pdf (3.8 MB)
Item type 紀要論文 / Departmental Bulletin Paper(1)
公開日 2007-05-10
タイトル
タイトル Usefulness of the Outpatient Chemotherapy Regimen of S-1 Followed by Weekly Paclitaxel for Far Advanced Gastric Cancer
タイトル
タイトル Usefulness of the Outpatient Chemotherapy Regimen of S-1 Followed by Weekly Paclitaxel for Far Advanced Gastric Cancer
言語 en
言語
言語 eng
キーワード
主題Scheme Other
主題 S-1
キーワード
主題Scheme Other
主題 Paclitaxel
キーワード
主題Scheme Other
主題 gastric cancer
キーワード
主題Scheme Other
主題 quality of life
キーワード
主題Scheme Other
主題 quality-adjusted survival analysis
資源タイプ
資源 http://purl.org/coar/resource_type/c_6501
タイプ departmental bulletin paper
著者 FURUKAWA, Koichi

× FURUKAWA, Koichi

WEKO 51770

FURUKAWA, Koichi

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WATANABE, Kazuhiko

× WATANABE, Kazuhiko

WEKO 51771

WATANABE, Kazuhiko

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ABE, Yukihiro

× ABE, Yukihiro

WEKO 51772

ABE, Yukihiro

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AIBA, Tuneo

× AIBA, Tuneo

WEKO 51773

AIBA, Tuneo

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IKARASHI, Kentarou

× IKARASHI, Kentarou

WEKO 51774

IKARASHI, Kentarou

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HATA, Koujiro

× HATA, Koujiro

WEKO 51775

HATA, Koujiro

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Ho, Nichau

× Ho, Nichau

WEKO 51776

Ho, Nichau

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TSUKIOKA, Satosi

× TSUKIOKA, Satosi

WEKO 51777

TSUKIOKA, Satosi

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抄録
内容記述タイプ Abstract
内容記述 To evaluate outpatient treatment, as well as the clinical effect of 1M tegafur-0.4M gimestat-1M otastat potassium(S-1) followed by weekly Paclitaxel(PTX) for patients with far advanced inoperable gastric cancer, we analyzed retrospectively the appropriateness of outpatient anticancer chemotherapy from the standards of overall survival and time without symptom and toxicity(TWiST) as a quality-adjusted survival analysis. A total of 18 patients with advanced inoperable gastric cancer were treated with S-1 as first line single-agent chemotherapy from May 1, 2000 to September 30, 2000 at the Niigata City General Hospital. S-1 (60mg-120mg/m^2/orally twice daily on Days 1-28 followed by a 14 days rest/course) was repeated until progression of the disease. After the first line was completed, a second line, PTX (60mg-80mg/m^2/infused on Day 1/week, three weeks and withdrawal for a week), was started two weeks later. PTX was repeated until progression of the disease. No severe adverse events (≧National Cancer Institute Common Toxicity Criteria ((NCICTC) grade 3) were observed. The median survival time (MST) overall including the first line and second line was 295 days. The hospitalization period was 60.0 days throughout the median of the total hospital stay and the rate was 25.6% in overall survival. There was no significant difference by histological type, metastasis, liver metastasis, or peritoneal dissemination. The median duration of TWiST as quality-adjusted survival analysis was 353 days in good performance status (PS) and 72 days in poor PS. S-1 followed by weekly PTX for various advanced inoperable gastric cancers appears to be a promising, appropriate, and well-tolerated anticancer chemotherapy regimen in an outpatient setting.
書誌情報 Acta medica et biologica
en : Acta medica et biologica

巻 53, 号 3, p. 73-77, 発行日 2005-09
出版者
出版者 Niigata University School of Medicine
ISSN
収録物識別子タイプ ISSN
収録物識別子 05677734
書誌レコードID
収録物識別子タイプ NCID
収録物識別子 AA00508361
著者版フラグ
値 publisher
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