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特発性ネフローゼ症候群における骨代謝
http://hdl.handle.net/10191/35495
http://hdl.handle.net/10191/3549532c19787-4baa-47c6-b048-cb588a8a674a
名前 / ファイル | ライセンス | アクション |
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100(10)_602-613.pdf (930.4 kB)
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Item type | 紀要論文 / Departmental Bulletin Paper(1) | |||||
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公開日 | 2015-12-11 | |||||
タイトル | ||||||
タイトル | 特発性ネフローゼ症候群における骨代謝 | |||||
タイトル | ||||||
言語 | en | |||||
タイトル | 特発性ネフローゼ症候群における骨代謝 | |||||
言語 | ||||||
言語 | jpn | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | hyperparathyroidism | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | NcAMP | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | free Hydroxyproline | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Bone mineral Analyzer | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Microdensitometer | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | 副甲状腺機能亢進症 | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | 腎性cAMP | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | フリーハイドロキシプロリン | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | 骨塩分析 | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | マイクロデンシトメーター | |||||
資源タイプ | ||||||
資源 | http://purl.org/coar/resource_type/c_6501 | |||||
タイプ | departmental bulletin paper | |||||
その他のタイトル | ||||||
その他のタイトル | Bone Metabolism of Children with Idiopathic Nephrotic Syndrome | |||||
著者 |
渡辺, 繁子
× 渡辺, 繁子 |
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著者別名 | ||||||
識別子 | 146558 | |||||
識別子Scheme | WEKO | |||||
姓名 | Watanabe, Shigeko | |||||
抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Children with nephrotic syndrome are frequently at risk for osteodystrophy due to secondary hyperparathyroidism. Severe proteinuria is accompanied by loss of 25-OH-Vit. D3, which causes hyperparathyroidism following hypocalcemia. On the other hand, administred glucocorticoid suppresses protein synthesis in osteoblasts to cause osteoporosis, and disturbs absorption of calcium in the intestine, which also leads to hyperparathyroidism. In this study 66 children with nephrotic syndrome were examined to elucidate bone metabolism associated with proteinuria and glucocorticoid therapy. Children with nephrotic syndrome showed high free hydroxyproline in urine(a parameter of turnover of the bone)and high NcAMP(which correlates with PTH), suggesting that administration of glucocorticoid for 1.5 to 2 months might cause secondary hyperparathyroidism. In children with nephrotic syndrome, the more glucocorticoid was given, the less bone mineral content was. These findings suggest that measurement of free Hyp and NcAMP, and analysis of bone construction with bone mineral analyzer or microdensitometer may be useful to estimate bone metabolism in children with nephrotic syndrome. | |||||
書誌情報 |
新潟医学会雑誌 en : 新潟医学会雑誌 巻 100, 号 10, p. 602-613, 発行日 1986-10 |
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出版者 | ||||||
出版者 | 新潟医学会 | |||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 00290440 | |||||
書誌レコードID | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AN00182415 | |||||
著者版フラグ | ||||||
値 | publisher |