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4) B型肝炎ウイルスの複製・増殖機構(シンポジウム 各科領域におけるウイルス病学の進歩, 第449回新潟医学会)
http://hdl.handle.net/10191/34754
http://hdl.handle.net/10191/34754105f8aa8-6fc4-4300-8e30-18e9713abfcf
名前 / ファイル | ライセンス | アクション |
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104(10)_823-826.pdf (1.2 MB)
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Item type | 紀要論文 / Departmental Bulletin Paper(1) | |||||
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公開日 | 2015-11-25 | |||||
タイトル | ||||||
タイトル | 4) B型肝炎ウイルスの複製・増殖機構(シンポジウム 各科領域におけるウイルス病学の進歩, 第449回新潟医学会) | |||||
タイトル | ||||||
言語 | en | |||||
タイトル | 4) B型肝炎ウイルスの複製・増殖機構(シンポジウム 各科領域におけるウイルス病学の進歩, 第449回新潟医学会) | |||||
言語 | ||||||
言語 | jpn | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | hepatitis B virus (HBV) carrier | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | HBV genome replication | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | extrachromosomal HBV DNA | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | integrated HBV DNA | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | B型肝炎ウイルスキャリア | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | HBウイルス遺伝子増殖 | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | 染色体外性HBウイルス DNA | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | 組込型HBウイルスDNA | |||||
資源タイプ | ||||||
資源 | http://purl.org/coar/resource_type/c_6501 | |||||
タイプ | departmental bulletin paper | |||||
その他のタイトル | ||||||
その他のタイトル | A Molecular Mechanism of Replication of Hepatits B Virus Genome(Recent Progress in Medical Virology of Five Etiologies) | |||||
著者 |
小方, 則夫
× 小方, 則夫 |
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著者別名 | ||||||
識別子 | 133575 | |||||
識別子Scheme | WEKO | |||||
姓名 | Ogata, Norio | |||||
抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Replication process of hepatits B virus (HBV) genome contains a step of reverse transcription from pregenome RNA of 3.6 kb in length. To obtain further insights into the replication mechanism of HBV genome, we examined liver tissue specimens obtained from patients of HBV carrier for the molecular structures of the viral DNA using Southern blot hybridization technique. In the active replication phase of the virus genome, extrachromosomal viral DNAs in the forms of relaxed circle, partially double strand and single strand, were observed. In contrast, the inactive replication phase of the virus genome was characterized by the existence of supercoiled circular form and relaxed circular form. As for the integrated forms of HBV DNA into cellular DNA, head-to-tail tandemly repeated form was detected in both active and inactive relication phases in some patients. Results described were discussed from a viewpoit of possible structures of the "proviral" HBV DNA for the production of the pregenome RNA. | |||||
書誌情報 |
新潟医学会雑誌 en : 新潟医学会雑誌 巻 104, 号 10, p. 823-826, 発行日 1990-10 |
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出版者 | ||||||
出版者 | 新潟医学会 | |||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 00290440 | |||||
書誌レコードID | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AN00182415 | |||||
著者版フラグ | ||||||
値 | publisher |