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Changes in the Activities of Hydroxysteroid Dehydrogenases in Rabbit and Hamster Oocytes during Meiotic Maturation
http://hdl.handle.net/10191/25130
http://hdl.handle.net/10191/25130693ef385-8183-470b-9cc9-7ac46daed5df
名前 / ファイル | ライセンス | アクション |
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20_3_118-123.pdf (291.1 kB)
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Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2014-02-12 | |||||
タイトル | ||||||
タイトル | Changes in the Activities of Hydroxysteroid Dehydrogenases in Rabbit and Hamster Oocytes during Meiotic Maturation | |||||
タイトル | ||||||
言語 | en | |||||
タイトル | Changes in the Activities of Hydroxysteroid Dehydrogenases in Rabbit and Hamster Oocytes during Meiotic Maturation | |||||
言語 | ||||||
言語 | eng | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Rabbit oocyte | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Hamster oocyte | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Meiotic maturation | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Hydroxysteroid dehydrogenase | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Histochemistry | |||||
資源タイプ | ||||||
資源 | http://purl.org/coar/resource_type/c_6501 | |||||
タイプ | journal article | |||||
著者 |
Niimura, Sueo
× Niimura, Sueo× Kawakami, Shin-ya |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | The activities of hydroxysteroid dehydrogenases (HSDs) were histochemically demonstrated in rabbit and hamster oocytes in the process of maturation, and the changes in steroid metabolism during meiotic maturation were examined. In rabbits, the percentages of oocytes showing the activities of Δ5-3β-HSD (with DHEA as the substrate), 17β-HSD (testosterone) and 20β-HSD (20β-hydroxyprogesterone) were always high and did not change during maturation, whereas those showing the activities of Δ5-3β-HSD (pregnenolone and 17α-hydroxy-pregnenolone), 17 β-HSD (estradiol-17β), 20α-HSD (20 α-hydroxyprogesterone) and 20β-HSD (17α-hydroxyprogesterone) decreased as the time after the hCG injection was prolonged. On the other hand, the activities of Δ5-3β-HSD, 17 β-HSD, 20α-HSD and 20β-HSD with eight substrates were almost always observed in hamster oocytes from 0 to 13 hrs after the hCG injection. The present findings suggested that the metabolic abilities of 20β-hydroxyprogesterone and androgen are constantly present in rabbit oocytes in the process of maturation, whereas those of progesterone, 17α-hydroxyprogesterone, 17α, 20β-dihydroxyprogesterone, 20α-hydroxyprogesterone and estrogen decrease during maturation. And it was also confirmed in hamster oocytes that the metabolic abilities of progesterone, 17α-hydroxyprogesterone, 17α, 20β-dihydroxyprogesterone, 20α-hydroxyprogesterone, 20β-hydroxyprogesterone, estrogen and androgen are always present and do not vary with maturation. | |||||
書誌情報 |
Journal of mammalian ova research en : Journal of mammalian ova research 巻 20, 号 3, p. 118-123, 発行日 2003 |
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出版者 | ||||||
出版者 | 日本哺乳動物卵子学会 | |||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 13417738 | |||||
書誌レコードID | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AN10548943 | |||||
DOI | ||||||
識別子タイプ | DOI | |||||
関連識別子 | info:doi/10.1274/jmor.20.118 | |||||
権利 | ||||||
権利情報 | 本文データは学協会の許諾に基づきJ-Stageから複製したものである | |||||
著者版フラグ | ||||||
値 | publisher | |||||
異版である | ||||||
関連タイプ | isVersionOf | |||||
識別子タイプ | URI | |||||
関連識別子 | https://www.jstage.jst.go.jp/article/jmor/20/3/20_3_118/_pdf |