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Pancreatic Weakness in Zucker Fatty Rats, a Genetic Obese Model
http://hdl.handle.net/10191/30616
http://hdl.handle.net/10191/3061651d6a5e4-7b6f-46eb-98eb-29f750a60381
名前 / ファイル | ライセンス | アクション |
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9_23_2963-2968.pdf (321.5 kB)
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Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2014-12-01 | |||||
タイトル | ||||||
タイトル | Pancreatic Weakness in Zucker Fatty Rats, a Genetic Obese Model | |||||
タイトル | ||||||
言語 | en | |||||
タイトル | Pancreatic Weakness in Zucker Fatty Rats, a Genetic Obese Model | |||||
言語 | ||||||
言語 | eng | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Diabetes | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | pancreas | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | streptozotocin | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Zf rat | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | dysfunction | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | weakness | |||||
資源タイプ | ||||||
資源 | http://purl.org/coar/resource_type/c_6501 | |||||
タイプ | journal article | |||||
著者 |
Ohta, Takeshi
× Ohta, Takeshi× Miyajima, Katsuhiro× Yamada, Takahisa |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Pancreatic dysfunction is a pivotal factor on incidence and development of diabetes mellitus and especially, the pancreatic weakness is a key defect contributing to diabetes mellitus. In this study, we investigated the pancreatic weakness in obese Zucker Fatty (ZF) rats. Different doses of Streptozotocin (STZ) were administered to ZF rats and the biochemical and the pancreatic related parameters were examined. Wistar rats were used as control animals. Before STZ injection, ZF rats showed a tendency to increase of insulinogenic index as compared with that in Wistar rats but the disposition index in ZF rats was significantly decreased as compared with that in Wistar rats. Moreover, the islets of STZ-untreated ZF rats were larger and had irregular boundaries. ZF rats treated with STZ at a dose level of 20 mg kg-1 were diabetic within one week after the treatment whereas Wistar rats got the diabetic after 30 mg kg-1 STZ was received. | |||||
書誌情報 |
Journal of animal and veterinary advances en : Journal of animal and veterinary advances 巻 9, 号 23, p. 2963-2968, 発行日 2010-12 |
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出版者 | ||||||
出版者 | Medwell Journals | |||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 16805593 | |||||
DOI | ||||||
識別子タイプ | DOI | |||||
関連識別子 | info:doi/10.3923/javaa.2010.2963.2968 | |||||
権利 | ||||||
権利情報 | Copyright(C)2010 Medwell Journals | |||||
著者版フラグ | ||||||
値 | publisher | |||||
異版である | ||||||
関連タイプ | isVersionOf | |||||
識別子タイプ | URI | |||||
関連識別子 | http://docsdrive.com/pdfs/medwelljournals/javaa/2010/2963-2968.pdf |