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1)退行期骨粗鬆症の病態(シンポジウム 骨粗鬆症の病態・治療・予防, 第493回新潟医学会)
http://hdl.handle.net/10191/40470
http://hdl.handle.net/10191/4047030c6826c-bc4b-41e7-beba-696cd13bb1ab
名前 / ファイル | ライセンス | アクション |
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108(11)_804-810.pdf (1.0 MB)
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Item type | 紀要論文 / Departmental Bulletin Paper(1) | |||||
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公開日 | 2016-03-29 | |||||
タイトル | ||||||
タイトル | 1)退行期骨粗鬆症の病態(シンポジウム 骨粗鬆症の病態・治療・予防, 第493回新潟医学会) | |||||
タイトル | ||||||
言語 | en | |||||
タイトル | 1)退行期骨粗鬆症の病態(シンポジウム 骨粗鬆症の病態・治療・予防, 第493回新潟医学会) | |||||
言語 | ||||||
言語 | jpn | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | involutinal osteoporosis | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | vitamin D | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | PTH | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | estrogen | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | bone turnover | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | 退行期骨粗鬆症 | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | ビタミンD | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | 上皮小体ホルモン | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | エストロゲン | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | 骨代謝回転 | |||||
資源タイプ | ||||||
資源 | http://purl.org/coar/resource_type/c_6501 | |||||
タイプ | departmental bulletin paper | |||||
その他のタイトル | ||||||
その他のタイトル | Pathomechanism of Involutional Osteoporosis (Pathogenesis, Treatment and Prevention of Osteoporosis) | |||||
著者 |
谷澤, 龍彦
× 谷澤, 龍彦 |
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著者別名 | ||||||
識別子 | 117907 | |||||
識別子Scheme | WEKO | |||||
姓名 | Tanizawa, Tatsuhiko | |||||
抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Bone loss enhanced by menopause and aging is recognized as involutional osteoporosis. Although the pathomechanism of this disease is considered to be multifactorial, estrogen depletion seems to be an initiating event causing bone loss. Estrogen receptors are found in rodent and human osteoblast like cells as well as in avian osteoclasts suggesting that estrogen can directly act on skeletal tissue. Furthermore, estrogen defficiency causes not only systemic changes of PTH and/or vitamin D metabolism but also changes of local bone resorbing factors released from monocytes. Aging is the additional causative factor of bone loss. Reduction of calcium absorption from gut becomes more serious long after menopause. Synthesis of active vitamin D in kidney is also reduced. Malabsorption of calcium may result in hyperparathyroid function for some period of time in elderly people. But since this state is likely to stabilize with time, bone turnover seems to be lowered with decreased number of osteoblasts. | |||||
書誌情報 |
新潟医学会雑誌 en : 新潟医学会雑誌 巻 108, 号 11, p. 804-810, 発行日 1994-11 |
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出版者 | ||||||
出版者 | 新潟医学会 | |||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 00290440 | |||||
書誌レコードID | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AN00182415 | |||||
著者版フラグ | ||||||
値 | publisher |