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グリオーマ細胞株におけるがん抑制遺伝子変化の解析
http://hdl.handle.net/10191/44417
http://hdl.handle.net/10191/44417f7f9ddfb-2bea-435a-94aa-d886e577d914
名前 / ファイル | ライセンス | アクション |
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111(1)_47-56.pdf (1.9 MB)
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Item type | 紀要論文 / Departmental Bulletin Paper(1) | |||||
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公開日 | 2016-10-21 | |||||
タイトル | ||||||
タイトル | グリオーマ細胞株におけるがん抑制遺伝子変化の解析 | |||||
タイトル | ||||||
言語 | en | |||||
タイトル | グリオーマ細胞株におけるがん抑制遺伝子変化の解析 | |||||
言語 | ||||||
言語 | jpn | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Glioma | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Brain tumor | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Tumor suppressor gene | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | p16 gene | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | p15 gene | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | p53 gene | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | p21 gene | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | グリオーマ | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | 脳腫瘍 | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | がん抑制遺伝子 | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | p16 遺伝子 | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | p15 遺伝子 | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | p53 遺伝子 | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | p21 遺伝子 | |||||
資源タイプ | ||||||
資源 | http://purl.org/coar/resource_type/c_6501 | |||||
タイプ | departmental bulletin paper | |||||
その他のタイトル | ||||||
その他のタイトル | Analysis of Tumor Suppressor Gene Alterations in Human Glioma Cell Lines | |||||
著者 |
張, 淑靖
× 張, 淑靖× 熊西, 敏郎 |
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著者別名 | ||||||
識別子 | 111503 | |||||
識別子Scheme | WEKO | |||||
姓名 | Zhang, Shu-Jing | |||||
著者別名 | ||||||
識別子 | 111504 | |||||
識別子Scheme | WEKO | |||||
姓名 | Kumanishi, Toshiro | |||||
抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Ten glioma cell lines were examined for alterations of the p16, p15 and p53 genes, which were tumor suppressor genes with direct or indirect CDK inhibitory functions. All the cell lines showed abnormalities in at least 1 gene, often in 2 or 3 genes coincidentally, suggesting that dysfunction of these genes is closely related to glioma cell growth. On examination of the primary tumor tissues, the same alterations of the p16/p15 and p53 genes as detected in the cell lines were demonstrated in all 6 cases examined, p16/p15 gene deletion in 1, p16 gene mutation in 1 and p53 gene mutations in 5 cases. This suggested that the p16/p15 and p53 gene alterations and their combinations in at least some glioma cell lines reflected those in the primary glioma tissues. | |||||
書誌情報 |
新潟医学会雑誌 en : 新潟医学会雑誌 巻 111, 号 1, p. 47-56, 発行日 1997-01 |
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出版者 | ||||||
出版者 | 新潟医学会 | |||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 00290440 | |||||
書誌レコードID | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AN00182415 | |||||
著者版フラグ | ||||||
値 | publisher |