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川崎病におけるアンギオテンシンI変換酵素遺伝子多型と冠動脈病変合併に関する検討
http://hdl.handle.net/10191/45761
http://hdl.handle.net/10191/45761b7ec233b-1b8b-475a-96a3-048396da325c
名前 / ファイル | ライセンス | アクション |
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112(3)_144-150.pdf (986.3 kB)
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Item type | 紀要論文 / Departmental Bulletin Paper(1) | |||||
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公開日 | 2017-01-24 | |||||
タイトル | ||||||
タイトル | 川崎病におけるアンギオテンシンI変換酵素遺伝子多型と冠動脈病変合併に関する検討 | |||||
タイトル | ||||||
言語 | en | |||||
タイトル | 川崎病におけるアンギオテンシンI変換酵素遺伝子多型と冠動脈病変合併に関する検討 | |||||
言語 | ||||||
言語 | jpn | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Kawasaki disease | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | coronary artery aneurysm | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | ACE polymorphism | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | 川崎病 | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | 冠動脈瘤 | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | ACE遺伝子多型 | |||||
資源タイプ | ||||||
資源 | http://purl.org/coar/resource_type/c_6501 | |||||
タイプ | departmental bulletin paper | |||||
その他のタイトル | ||||||
その他のタイトル | Study of Angiotensin I Converting Enzyme Polymorphism in Relation to Coronary Artery Aneurysm Formation in Kawasaki Disease | |||||
著者 |
竹内, 菊博
× 竹内, 菊博 |
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著者別名 | ||||||
識別子 | 106685 | |||||
識別子Scheme | WEKO | |||||
姓名 | Takeuchi, Kikuhiro | |||||
抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | ACE (angiotensin I couverting enzyme) gene was examined by polymerase chain reaction (PCR) in 36 subjects who had a past history of Kawasaki disease (16 without coronary aneurysm 20 with coronary aneurysm). A polymorphism in the ACE gene was characterized by three genotypes:two D alleles (genotype DD), two I alleles (genotype II), and heterozygotes allele (genotype DI), Genotype II was found in 65 % of the subjects with aneurysm and 12.5 % of those without aneurysm (p < 0.01, Odds ratio 13.0, 95 % confidence intervals). Although the mechanism of aneurysm formation in Kawasaki disease is unknown, the present study showed that the frequency of II genotype is significantly higher in subjects with Kawasaki disease and coronary aneurysm than in those without aneurysm. These findings suggest that II genotype may contribute to vascular dilatation, contrary to the predisposition of DD genotype to vascular stenosis. | |||||
書誌情報 |
新潟医学会雑誌 en : 新潟医学会雑誌 巻 112, 号 3, p. 144-150, 発行日 1998-03 |
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出版者 | ||||||
出版者 | 新潟医学会 | |||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 00290440 | |||||
書誌レコードID | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AN00182415 | |||||
著者版フラグ | ||||||
値 | publisher |