WEKO3
アイテム
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Patient: A Japanese 11-year-old girl complained of poor visual acuity. There was no parental consanguinity in her family. The corrected visual acuity was 0.7 in both eyes. No abnormal finding was observed in both fundi. Methods: The patient underwent full-field ERGs. Rod and cone a-waves were analyzed using photoreceptor models. The derived PII responses were analyzed using a technique described by Hood and Birch. Results: In the photopic ERG, responses to single flash and 30-Hz flicker were attenuated. In the scotopic ERG, b-wave was supernormal in amplitude in response to intense flashes, but smaller than normal and markedly delayed over a lower range of flash intensities. By the PIII analysis, phototransductions (values of S) of both rod and cone were remarkably decreased. The derived PII responses for this patient were larger than the responses for normal subjects, and the onset of the PII responses in this patient are significantly delayed compared to those in normal subjects. 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PIII and derived PII analysis in a patient with retinal dysfunction with supernormal scotopic ERG
http://hdl.handle.net/10191/1175
http://hdl.handle.net/10191/117550768448-2a14-412b-bbfd-17526b8fa54e
名前 / ファイル | ライセンス | アクション |
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24_0002.pdf (222.9 kB)
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Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2007-04-23 | |||||
タイトル | ||||||
言語 | en | |||||
タイトル | PIII and derived PII analysis in a patient with retinal dysfunction with supernormal scotopic ERG | |||||
言語 | ||||||
言語 | eng | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Cone | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | electroretinogram | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | phototransduction | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | retinal dysfunction | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | rod | |||||
資源タイプ | ||||||
資源 | http://purl.org/coar/resource_type/c_6501 | |||||
タイプ | journal article | |||||
著者 |
Tanimoto, Naoyuki
× Tanimoto, Naoyuki× Usui, Tomoaki× Ichibe, Mineo× Takagi, Mineo× Hasegawa, Shigeru× Abe, Haruki |
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著者別名 | ||||||
識別子 | 4737 | |||||
識別子Scheme | WEKO | |||||
姓名 | 高木, 峰夫 | |||||
抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Purpose: To present electroretinographic (ERG) findings in a patient with retinal dysfunction with supernormal scotopic ERG, and to analyze rod and cone PIII components and rod inner nuclear layer (derived PII) responses. Patient: A Japanese 11-year-old girl complained of poor visual acuity. There was no parental consanguinity in her family. The corrected visual acuity was 0.7 in both eyes. No abnormal finding was observed in both fundi. Methods: The patient underwent full-field ERGs. Rod and cone a-waves were analyzed using photoreceptor models. The derived PII responses were analyzed using a technique described by Hood and Birch. Results: In the photopic ERG, responses to single flash and 30-Hz flicker were attenuated. In the scotopic ERG, b-wave was supernormal in amplitude in response to intense flashes, but smaller than normal and markedly delayed over a lower range of flash intensities. By the PIII analysis, phototransductions (values of S) of both rod and cone were remarkably decreased. The derived PII responses for this patient were larger than the responses for normal subjects, and the onset of the PII responses in this patient are significantly delayed compared to those in normal subjects. Conclusions: The ophthalmological findings in this patient are consistent with previous publications of this disease. Although it has been reported that the sites of disease action were beyond the outer segment (values of S were within the normal range), our results suggest that photoreceptors could be involved in sites of disease action in at least some patients with this disease. | |||||
書誌情報 |
Documenta ophthalmologica en : Documenta ophthalmologica 巻 110, 号 2-3, p. 219-226, 発行日 2005-03 |
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ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 00124486 | |||||
書誌レコードID | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AA00629399 | |||||
PubMed番号 | ||||||
識別子タイプ | PMID | |||||
関連識別子 | 16328930 | |||||
DOI | ||||||
識別子タイプ | DOI | |||||
関連識別子 | info:doi/10.1007/s10633-005-7861-8 | |||||
権利 | ||||||
権利情報 | Springer | |||||
著者版フラグ | ||||||
値 | author |