WEKO3
-
RootNode
アイテム
Association of a single nucleotide polymorphism in akirin 2 gene with marbling in Japanese Black beef cattle
http://hdl.handle.net/10191/30611
http://hdl.handle.net/10191/306118d7a6e8f-b93d-487c-a037-016c30f9b3b5
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
2_131.pdf (192.1 kB)
|
|
| Item type | 学術雑誌論文 / Journal Article(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2014-12-01 | |||||
| タイトル | ||||||
| タイトル | Association of a single nucleotide polymorphism in akirin 2 gene with marbling in Japanese Black beef cattle | |||||
| タイトル | ||||||
| タイトル | Association of a single nucleotide polymorphism in akirin 2 gene with marbling in Japanese Black beef cattle | |||||
| 言語 | en | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源 | http://purl.org/coar/resource_type/c_6501 | |||||
| タイプ | journal article | |||||
| 著者 |
Sasaki, Seiki
× Sasaki, Seiki× Yamada, Takahisa× Sukegawa, Shin× Miyake, Takeshi× Fujita, Tatsuo× Morita, Mitsuo× Ohta, Takeshi× Takahagi, Youichi× Murakami, Hiroshi× Morimatsu, Fumiki× Sasaki, Yoshiyuki |
|||||
| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | Background: Marbling defined by the amount and distribution of intramuscular fat, so-called Shimofuri, is an economically important trait of beef cattle in Japan. The c17-25 expressed sequence tag (EST) has been previously shown to possess expression difference in musculus longissimus muscle between low-marbled and high-marbled steer groups, and to be located within genomic region of a quantitative trait locus for marbling. Thus, the akirin 2 (AKIRIN2) gene containing the c17-25 EST sequence was considered as a positional functional candidate for the gene responsible for marbling. In this study, we explored single nucleotide polymorphism (SNP) in the AKIRIN2 and analyzed association of the SNP with marbling. Findings: A SNP in the 3' untranslated region of the AKIRIN2, referred to as c.*188G>A, was the only difference detected between high- and low-marbled steer groups. The SNP was associated with marbling in 3 experiments using 100 sires (P = 0.041), 753 paternal half-sib progeny steers from 4 sires heterozygous for the c.*188G>A (P = 0.005), and 730 paternal half-sib progeny steers from 3 sires homozygous for the A allele at the c.*188G>A (P = 0.047), in Japanese Black beef cattle. The effect of genotypes of the SNP on subcutaneous fat thickness was not statistically significant (P > 0.05).\nConclusion: These findings suggest that the AKIRIN2 SNP polymorphism is associated with marbling and may be useful for effective marker-assisted selection to increase the levels of marbling in Japanese Black beef cattle. | |||||
| 書誌情報 |
BMC research notes en : BMC research notes 巻 2, p. 131-1-131-5, 発行日 2009-07 |
|||||
| 出版者 | ||||||
| 出版者 | BioMed Central | |||||
| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 17560500 | |||||
| DOI | ||||||
| 識別子タイプ | DOI | |||||
| 関連識別子 | info:doi/10.1186/1756-0500-2-131 | |||||
| 権利 | ||||||
| 権利情報 | (C) 2009 Yamada et al; licensee BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. | |||||
| 著者版フラグ | ||||||
| 値 | publisher | |||||
| 異版である | ||||||
| 関連タイプ | isVersionOf | |||||
| 識別子タイプ | URI | |||||
| 関連識別子 | http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2715414/pdf/1756-0500-2-131.pdf | |||||
