WEKO3
アイテム
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ActivinA/EDF (Erythroid Differentiation Factor) のヒト造血幹細胞分化に及ぼす影響
http://hdl.handle.net/10191/38180
http://hdl.handle.net/10191/38180ba3a14fe-5fe7-4a00-b9f5-ceb3a9dc7ba8
名前 / ファイル | ライセンス | アクション |
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108(4)_301-308.pdf (1.6 MB)
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Item type | 紀要論文 / Departmental Bulletin Paper(1) | |||||
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公開日 | 2016-02-10 | |||||
タイトル | ||||||
タイトル | ActivinA/EDF (Erythroid Differentiation Factor) のヒト造血幹細胞分化に及ぼす影響 | |||||
タイトル | ||||||
言語 | en | |||||
タイトル | ActivinA/EDF (Erythroid Differentiation Factor) のヒト造血幹細胞分化に及ぼす影響 | |||||
言語 | ||||||
言語 | jpn | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | EDF (erythroid differentiation factor) | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | erythropoiesis | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | megakaryocytic differentiation | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | cyclo-oxygenase | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | cytokine | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | 赤血球分化 | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | 巨核芽球分化 | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | サイクロオキシゲナーゼ | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | 造血因子 | |||||
資源タイプ | ||||||
資源 | http://purl.org/coar/resource_type/c_6501 | |||||
タイプ | departmental bulletin paper | |||||
その他のタイトル | ||||||
その他のタイトル | Effects of ActivinA/EDF (Erythroid Differentiation Factor) on Differentiation of Human Hematopoietic Stem Cell | |||||
著者 |
後藤, 隆夫
× 後藤, 隆夫 |
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著者別名 | ||||||
識別子 | 120732 | |||||
識別子Scheme | WEKO | |||||
姓名 | Goto, Takao | |||||
抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | ActivinA/EDF (Erythroid Differentiation Factor) purified from the culture fluid of human monocytic cells (THP-1 cells) has shown to be potential to a differentiation murine erythroleukemic cells (Friend cells). In this study, we demonstrated that ActivinA/EDF increases in the number of hemoglobin positive cells in human erythroleukemia cell lines without the reduction of cell proliferation. In addition, it enhances erythroid colony formation from human erythroid progenitors of normal and MDS (myelodysplastic syndrome) in vitro. On the other hand, cyclo-oxygenase (CO) mRNA levels increase in liquid culture of human erythroleukemia cell lines after incubation with ActivinA/EDF by RT-PCR (reverse transcription-polymerase chain reaction). These results suggest that ActivinA/EDF possibly acts as an important cytokine of erythropoiesis and megakaryocytic differentiation of human hematopoietic stem cell. | |||||
書誌情報 |
新潟医学会雑誌 en : 新潟医学会雑誌 巻 108, 号 4, p. 301-308, 発行日 1994-04 |
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出版者 | ||||||
出版者 | 新潟医学会 | |||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 00290440 | |||||
書誌レコードID | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AN00182415 | |||||
著者版フラグ | ||||||
値 | publisher |