We had already reported the technical feasibility and clinical safety of 13.56 MHz Radiofrequency(RF)interstitial hyperthermia for brain tumors. In this study, we analyzed retrospectively the therapeutic effects of interstitial hyperthermia on CT scans. The RF interstitial hyperthermia was performed on 30 patients with malignant gliomas. Intracranial electrodes, RF antennas, were inserted into the tumor. The edge of enhanced lesion on CT scan was heated at 43℃ for 60min. The heating was repeated 3-6 times with/without radiochemotherapy. No major side effects occured. The results showed CRh in 6, PRh in 14 and NRh in 10 cases on CT evaluation. The RF interstitial hyperthermia seemed to be effective in treatment of malignant gliomas.